| Literature DB >> 29704626 |
S Pollett1, M C Melendrez2, I Maljkovic Berry2, S Duchêne3, H Salje4, D A T Cummings5, R G Jarman2.
Abstract
Dengue virus (DENV) causes a profound burden of morbidity and mortality, and its global burden is rising due to the co-circulation of four divergent DENV serotypes in the ecological context of globalization, travel, climate change, urbanization, and expansion of the geographic range of the Ae.aegypti and Ae.albopictus vectors. Understanding DENV evolution offers valuable opportunities to enhance surveillance and response to DENV epidemics via advances in RNA virus sequencing, bioinformatics, phylogenetic and other computational biology methods. Here we provide a scoping overview of the evolution and molecular epidemiology of DENV and the range of ways that evolutionary analyses can be applied as a public health tool against this arboviral pathogen.Entities:
Keywords: Dengue virus; Evolution; Molecular epidemiology; Phylogenetics
Mesh：
Year: 2018 PMID： 29704626 PMCID： PMC6396301 DOI： 10.1016/j.meegid.2018.04.032
Source DB: PubMed Journal: Infect Genet Evol ISSN： 1567-1348 Impact factor: 3.342