Namaitijiang Maimaiti1, Zafar Ahmed2, Zaleha Md Isa3, Hasanain Faisal Ghazi4, Syed Aljunid2. 1. International Institute for Global Health, United Nations University, Kuala Lumpur, Malaysia; Department of Community Health, Faculty of Medicine, UKM. Electronic address: nametjan@unu.edu. 2. International Institute for Global Health, United Nations University, Kuala Lumpur, Malaysia; International Centre for Case-Mix and Clinical Coding, UKM Medical Centre. 3. Department of Community Health, Faculty of Medicine, UKM. 4. International Institute for Global Health, United Nations University, Kuala Lumpur, Malaysia; Department of Community Health, Faculty of Medicine, UKM.
Abstract
OBJECTIVE: To measure the clinical burden of invasive pneumococcal disease (IPD) in selected developing countries. METHODS: This is an extensive literature review of published articles on IPD in selected developing countries from East Asia, South Asia, Middle East, sub-Saharan Africa, and Latin America. We reviewed all the articles retrieved from the knowledge bases that were published between the years 2000 and 2010. RESULTS: After applying the inclusion, exclusion, and quality criteria, the comprehensive review of the literature yielded 10 articles with data for pneumococcal meningitis, septicemia/bacteremia, and pneumonia. These selected articles were from 10 developing countries from five different regions. Out of the 10 selected articles, 8 have a detailed discussion on IPD, one of them has s detailed discussion on bacteremia and meningitis, and another one has discussed pneumococcal bacteremia. Out of these 10 articles, only 5 articles discussed the case-fatality ratio (CFR). In our article review, the incidence of IPD ranged from less than 5/100,000 to 416/100,000 population and the CFR ranged from 12.2% to 80% in the developing countries. CONCLUSIONS: The review demonstrated that the clinical burden of IPD was high in the developing countries. The incidence of IPD and CFR varies from region to region and from country to country. The IPD burden was highest in sub-Saharan African countries followed by South Asian countries. The CFR was low in high-income countries than in low-income countries.
OBJECTIVE: To measure the clinical burden of invasive pneumococcal disease (IPD) in selected developing countries. METHODS: This is an extensive literature review of published articles on IPD in selected developing countries from East Asia, South Asia, Middle East, sub-Saharan Africa, and Latin America. We reviewed all the articles retrieved from the knowledge bases that were published between the years 2000 and 2010. RESULTS: After applying the inclusion, exclusion, and quality criteria, the comprehensive review of the literature yielded 10 articles with data for pneumococcal meningitis, septicemia/bacteremia, and pneumonia. These selected articles were from 10 developing countries from five different regions. Out of the 10 selected articles, 8 have a detailed discussion on IPD, one of them has s detailed discussion on bacteremia and meningitis, and another one has discussed pneumococcal bacteremia. Out of these 10 articles, only 5 articles discussed the case-fatality ratio (CFR). In our article review, the incidence of IPD ranged from less than 5/100,000 to 416/100,000 population and the CFR ranged from 12.2% to 80% in the developing countries. CONCLUSIONS: The review demonstrated that the clinical burden of IPD was high in the developing countries. The incidence of IPD and CFR varies from region to region and from country to country. The IPD burden was highest in sub-Saharan African countries followed by South Asian countries. The CFR was low in high-income countries than in low-income countries.
Authors: Catrin E Moore; Adam Giess; Sona Soeng; Poda Sar; Varun Kumar; Pheakdey Nhoung; Rachel Bousfield; Paul Turner; Nicole Stoesser; Nicholas P J Day; Christopher M Parry Journal: PLoS One Date: 2016-07-22 Impact factor: 3.240