INTRODUCTION: Dengue virus infection is the most common arthropod-borne disease worldwide with approximately 50 to 100 million cases of dengue infection occurring annually. Globally, dengue incidence has increased in the last 40 years, especially in Latin American and Caribbean (LAC) countries where the highest incidence is found. This systematic review aimed to present information on dengue disease burden and use of health resources in the LAC region in the last 15 years. METHODS: We searched the main international and regional databases and generic and academic Internet search engines. Gray literature was retrieved mainly from regional health ministries and Pan American Health Organization. A set of inclusion criteria was defined. RESULTS: We identified 2,041 articles of which 25 met these criteria, 13 for incidence and 12 for the use of resources and related costs. The pooled incidence of classic dengue fever was 72.1 cases per 100,000 persons-years in the 44 LAC countries analyzed (95% confidence interval 71.5-72.7), with an upward trend from 1995 up to 2010. Case-fatality ratio was highest in 1997 (0.12 [0.05-0.22]) and lowest in 2009, and the overall mortality was 0.02 per 100,000 people. More than 60% of the cases in the LAC region came from Brazil. The length of hospital stay ranged from 5 to 13 days. CONCLUSIONS: Activities to control dengue transmission in the region have been important but insufficient. The surveillance of dengue burden of disease and circulating strains help shape and evaluate the present and future health policies.
INTRODUCTION:Dengue virus infection is the most common arthropod-borne disease worldwide with approximately 50 to 100 million cases of dengue infection occurring annually. Globally, dengue incidence has increased in the last 40 years, especially in Latin American and Caribbean (LAC) countries where the highest incidence is found. This systematic review aimed to present information on dengue disease burden and use of health resources in the LAC region in the last 15 years. METHODS: We searched the main international and regional databases and generic and academic Internet search engines. Gray literature was retrieved mainly from regional health ministries and Pan American Health Organization. A set of inclusion criteria was defined. RESULTS: We identified 2,041 articles of which 25 met these criteria, 13 for incidence and 12 for the use of resources and related costs. The pooled incidence of classic dengue fever was 72.1 cases per 100,000 persons-years in the 44 LAC countries analyzed (95% confidence interval 71.5-72.7), with an upward trend from 1995 up to 2010. Case-fatality ratio was highest in 1997 (0.12 [0.05-0.22]) and lowest in 2009, and the overall mortality was 0.02 per 100,000 people. More than 60% of the cases in the LAC region came from Brazil. The length of hospital stay ranged from 5 to 13 days. CONCLUSIONS: Activities to control dengue transmission in the region have been important but insufficient. The surveillance of dengue burden of disease and circulating strains help shape and evaluate the present and future health policies.
Authors: Rashedul Islam; Mohammed Salahuddin; Md Salahuddin Ayubi; Tahmina Hossain; Apurba Majumder; Andrew W Taylor-Robinson; Abdullah Mahmud-Al-Rafat Journal: Virol Sin Date: 2015-10-20 Impact factor: 4.327
Authors: María José Arauz; Valéry Ridde; Libia Milena Hernández; Yaneth Charris; Mabel Carabali; Luis Ángel Villar Journal: PLoS One Date: 2015-02-06 Impact factor: 3.240
Authors: Stefan Flasche; Mark Jit; Isabel Rodríguez-Barraquer; Laurent Coudeville; Mario Recker; Katia Koelle; George Milne; Thomas J Hladish; T Alex Perkins; Derek A T Cummings; Ilaria Dorigatti; Daniel J Laydon; Guido España; Joel Kelso; Ira Longini; Jose Lourenco; Carl A B Pearson; Robert C Reiner; Luis Mier-Y-Terán-Romero; Kirsten Vannice; Neil Ferguson Journal: PLoS Med Date: 2016-11-29 Impact factor: 11.069
Authors: José Legorreta-Soberanis; Sergio Paredes-Solís; Arcadio Morales-Pérez; Elizabeth Nava-Aguilera; Felipe René Serrano-de Los Santos; Diana Lisseth Dimas-Garcia; Robert J Ledogar; Anne Cockcroft; Neil Andersson Journal: BMC Public Health Date: 2017-05-30 Impact factor: 3.295
Authors: José Legorreta-Soberanis; Sergio Paredes-Solís; Arcadio Morales-Pérez; Elizabeth Nava-Aguilera; Felipe René Serrano-de Los Santos; Belén Madeline Sánchez-Gervacio; Robert J Ledogar; Anne Cockcroft; Neil Andersson Journal: BMC Public Health Date: 2017-05-30 Impact factor: 3.295