Literature DB >> 29702533

Mouse Pancreatic Tumor Model Independent of Tumor Suppressor Gene Inactivation.

Mayumi Naramura1, Amarnath Natarajan.   

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Year:  2018        PMID: 29702533      PMCID: PMC5926800          DOI: 10.1097/MPA.0000000000001041

Source DB:  PubMed          Journal:  Pancreas        ISSN: 0885-3177            Impact factor:   3.327


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  5 in total

1.  An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice.

Authors:  Jaroslaw Daniluk; Yan Liu; Defeng Deng; Jun Chu; Haojie Huang; Sebastian Gaiser; Zobeida Cruz-Monserrate; Huamin Wang; Baoan Ji; Craig D Logsdon
Journal:  J Clin Invest       Date:  2012-03-12       Impact factor: 14.808

2.  KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.

Authors:  Jianhua Ling; Ya'an Kang; Ruiying Zhao; Qianghua Xia; Dung-Fang Lee; Zhe Chang; Jin Li; Bailu Peng; Jason B Fleming; Huamin Wang; Jinsong Liu; Ihor R Lemischka; Mien-Chie Hung; Paul J Chiao
Journal:  Cancer Cell       Date:  2012-01-17       Impact factor: 31.743

3.  Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice.

Authors:  Eleni Maniati; Maud Bossard; Natalie Cook; Juliana B Candido; Nia Emami-Shahri; Sergei A Nedospasov; Frances R Balkwill; David A Tuveson; Thorsten Hagemann
Journal:  J Clin Invest       Date:  2011-11-07       Impact factor: 14.808

Review 4.  Ductal pancreatic cancer in humans and mice.

Authors:  D A Tuveson; S R Hingorani
Journal:  Cold Spring Harb Symp Quant Biol       Date:  2005

Review 5.  Modifiable and non-modifiable risk factors for pancreatic cancer: A review.

Authors:  Shallu Midha; Saurabh Chawla; Pramod Kumar Garg
Journal:  Cancer Lett       Date:  2016-07-25       Impact factor: 8.679

  5 in total
  5 in total

1.  Dimers of isatin derived α-methylene-γ-butyrolactone as potent anti-cancer agents.

Authors:  Sandeep Rana; Smit Kour; Smitha Kizhake; Hannah M King; Jayapal Reddy Mallareddy; Adam J Case; Tom Huxford; Amarnath Natarajan
Journal:  Bioorg Med Chem Lett       Date:  2022-04-01       Impact factor: 2.940

2.  Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth.

Authors:  John Victor Napoleon; Satish Sagar; Sydney P Kubica; Lidia Boghean; Smit Kour; Hannah M King; Yogesh A Sonawane; Ayrianne J Crawford; Nagsen Gautam; Smitha Kizhake; Pawel A Bialk; Eric Kmiec; Jayapal Reddy Mallareddy; Prathamesh P Patil; Sandeep Rana; Sarbjit Singh; Janani Prahlad; Paul M Grandgenett; Gloria E O Borgstahl; Gargi Ghosal; Yazen Alnouti; Michael A Hollingsworth; Prakash Radhakrishnan; Amarnath Natarajan
Journal:  Proc Natl Acad Sci U S A       Date:  2022-04-27       Impact factor: 12.779

3.  Small molecule binding to inhibitor of nuclear factor kappa-B kinase subunit beta in an ATP non-competitive manner.

Authors:  John V Napoleon; Sarbjit Singh; Sandeep Rana; Mourad Bendjennat; Vikas Kumar; Smitha Kizhake; Nicholas Y Palermo; Michel M Ouellette; Tom Huxford; Amarnath Natarajan
Journal:  Chem Commun (Camb)       Date:  2021-05-11       Impact factor: 6.222

4.  Stapling proteins in the RELA complex inhibits TNFα-induced nuclear translocation of RELA.

Authors:  Smit Kour; Sandeep Rana; Smitha Kizhake; Dragana Lagundžin; David Klinkebiel; Jayapal Reddy Mallareddy; Tom Huxford; Nicholas T Woods; Amarnath Natarajan
Journal:  RSC Chem Biol       Date:  2021-10-28

5.  Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy.

Authors:  Satish Sagar; Sarbjit Singh; Jayapal Reddy Mallareddy; Yogesh A Sonawane; John V Napoleon; Sandeep Rana; Jacob I Contreras; Christabelle Rajesh; Edward L Ezell; Smitha Kizhake; Jered C Garrison; Prakash Radhakrishnan; Amarnath Natarajan
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  5 in total

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