Duo Huang1, Pak-Hei Chan1, Hoi-Lam She2, Chun Ka Wong1, Chi-Wai Ho1, Yang-Yang Cheng1, Esther W Chan3, Chern-En Chiang4, Chung-Wah Siu5. 1. Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China. 2. Department of Radiology, The University of Hong Kong, Hong Kong, China. 3. Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China. 4. General Clinical Research Center, Taipei Veterans General Hospital, Taipei City, Taiwan. 5. Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China. Electronic address: cwdsiu@hku.hk.
Abstract
INTRODUCTION: Current epidemiological data for venous thromboembolism (VTE) are derived primarily from Caucasian populations from North America. Little is known for other ethnic groups. This study aimed to describe the incidence, etiologies, and the secular trends of VTE in a Chinese population. MATERIALS AND METHODS: This was an observational study using a hospital VTE registry. RESULTS AND CONCLUSIONS: Between 2004 and 2016, 2214 patients (mean age 66.2 ± 17.4 years, 57.2% female) were hospitalized for a novel occurrence of venous thromboembolism. Of these, 1444 patients (65.2%) had deep venous thrombosis and 770 patients (34.8%) had pulmonary embolism. Over the 13-year period, there was an increasing trend in the incidence of VTE from 28.1 per 100,000 population per year in 2004 to 48.3 per 100,000 population per year in 2016. There has been a disproportional increase in the incidence of VTE among those aged 75 years or above. Etiologically, the most common cause of VTE was active malignancy with an incidence that increased from 34.8% in 2005 to 60.9% in 2014. In conclusion, the incidence of venous thromboembolism in Hong Kong appears to be lower than that in previous Caucasian series. Nonetheless there has been an increasing incidence of VTE over the past decade, primarily related to aging and malignancy.
INTRODUCTION: Current epidemiological data for venous thromboembolism (VTE) are derived primarily from Caucasian populations from North America. Little is known for other ethnic groups. This study aimed to describe the incidence, etiologies, and the secular trends of VTE in a Chinese population. MATERIALS AND METHODS: This was an observational study using a hospital VTE registry. RESULTS AND CONCLUSIONS: Between 2004 and 2016, 2214 patients (mean age 66.2 ± 17.4 years, 57.2% female) were hospitalized for a novel occurrence of venous thromboembolism. Of these, 1444 patients (65.2%) had deep venous thrombosis and 770 patients (34.8%) had pulmonary embolism. Over the 13-year period, there was an increasing trend in the incidence of VTE from 28.1 per 100,000 population per year in 2004 to 48.3 per 100,000 population per year in 2016. There has been a disproportional increase in the incidence of VTE among those aged 75 years or above. Etiologically, the most common cause of VTE was active malignancy with an incidence that increased from 34.8% in 2005 to 60.9% in 2014. In conclusion, the incidence of venous thromboembolism in Hong Kong appears to be lower than that in previous Caucasian series. Nonetheless there has been an increasing incidence of VTE over the past decade, primarily related to aging and malignancy.
Authors: Adam Cuker; Eric K Tseng; Holger J Schünemann; Pantep Angchaisuksiri; Clifton Blair; Kathryn Dane; Maria T DeSancho; David Diuguid; Daniel O Griffin; Susan R Kahn; Frederikus A Klok; Alfred Ian Lee; Ignacio Neumann; Ashok Pai; Marc Righini; Kristen M Sanfilippo; Deborah M Siegal; Mike Skara; Deirdra R Terrell; Kamshad Touri; Elie A Akl; Reyad Al Jabiri; Yazan Al Jabiri; Mary Boulos; Romina Brignardello-Petersen; Rana Charide; Luis E Colunga-Lozano; Karin Dearness; Andrea J Darzi; Samer G Karam; Gian Paolo Morgano; Rami Z Morsi; Binu A Philip; Yetiani Roldan Benitez; Adrienne Stevens; Karla Solo; Wojtek Wiercioch; Reem A Mustafa; Robby Nieuwlaat Journal: Blood Adv Date: 2022-09-13
Authors: Adam Cuker; Eric K Tseng; Robby Nieuwlaat; Pantep Angchaisuksiri; Clifton Blair; Kathryn Dane; Jennifer Davila; Maria T DeSancho; David Diuguid; Daniel O Griffin; Susan R Kahn; Frederikus A Klok; Alfred Ian Lee; Ignacio Neumann; Ashok Pai; Menaka Pai; Marc Righini; Kristen M Sanfilippo; Deborah Siegal; Mike Skara; Kamshad Touri; Elie A Akl; Imad Bou Akl; Mary Boulos; Romina Brignardello-Petersen; Rana Charide; Matthew Chan; Karin Dearness; Andrea J Darzi; Philipp Kolb; Luis E Colunga-Lozano; Razan Mansour; Gian Paolo Morgano; Rami Z Morsi; Atefeh Noori; Thomas Piggott; Yuan Qiu; Yetiani Roldan; Finn Schünemann; Adrienne Stevens; Karla Solo; Matthew Ventresca; Wojtek Wiercioch; Reem A Mustafa; Holger J Schünemann Journal: Blood Adv Date: 2021-02-09
Authors: Adam Cuker; Eric K Tseng; Robby Nieuwlaat; Pantep Angchaisuksiri; Clifton Blair; Kathryn Dane; Jennifer Davila; Maria T DeSancho; David Diuguid; Daniel O Griffin; Susan R Kahn; Frederikus A Klok; Alfred Ian Lee; Ignacio Neumann; Ashok Pai; Marc Righini; Kristen M Sanfilippo; Deborah Siegal; Mike Skara; Deirdra R Terrell; Kamshad Touri; Elie A Akl; Imad Bou Akl; Antonio Bognanni; Mary Boulos; Romina Brignardello-Petersen; Rana Charide; Matthew Chan; Karin Dearness; Andrea J Darzi; Philipp Kolb; Luis E Colunga-Lozano; Razan Mansour; Gian Paolo Morgano; Rami Z Morsi; Giovanna Muti-Schünemann; Atefeh Noori; Binu A Philip; Thomas Piggott; Yuan Qiu; Yetiani Roldan; Finn Schünemann; Adrienne Stevens; Karla Solo; Wojtek Wiercioch; Reem A Mustafa; Holger J Schünemann Journal: Blood Adv Date: 2021-10-26