| Literature DB >> 29702183 |
Kiarash Ghassaban1, Saifeng Liu2, Caihong Jiang3, E Mark Haacke4.
Abstract
Measuring iron content has practical clinical indications in the study of diseases such as Parkinson's disease, Huntington's disease, ferritinopathies and multiple sclerosis as well as in the quantification of iron content in microbleeds and oxygen saturation in veins. In this work, we review the basic concepts behind imaging iron using T2, T2*, T2', phase and quantitative susceptibility mapping in the human brain, liver and heart, followed by the applications of in vivo iron quantification in neurodegenerative diseases, iron tagged cells and ultra-small superparamagnetic iron oxide (USPIO) nanoparticles.Entities:
Keywords: Iron quantification; Iron tagged cells; Magnetic resonance imaging; Multiple sclerosis; Parkinson's disease; USPIO contrast agents
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Year: 2018 PMID: 29702183 DOI: 10.1016/j.neuroimage.2018.04.047
Source DB: PubMed Journal: Neuroimage ISSN: 1053-8119 Impact factor: 6.556