Nada Woodtli1, Michael von Wolff1, Norman Bitterlich2, Petra Stute3,4. 1. Department of Obstetrics and Gynecology, University of Bern, Bern, Switzerland. 2. Medizin & Service GmbH, Chemnitz, Germany. 3. Department of Obstetrics and Gynecology, University of Bern, Bern, Switzerland. petra.stute@insel.ch. 4. Department of Gynaecologic Endocrinology and Reproductive Medicine, University Women's Hospital, Effingerstrasse 102, 3010, Bern, Switzerland. petra.stute@insel.ch.
Abstract
PURPOSE: To assess the attitude towards ovarian tissue and oocyte cryopreservation for non-medical reasons. METHODS: Cross-sectional electronic survey in 248 Swiss women aged 15-35 years, nationally representative for educational level. RESULTS: Most women did not worry about an age-related fertility decline. Two-thirds of women would consider using hormone therapy (HT) for menopausal symptom relief although concerns about side effects and risks were still high. Acceptance of cryopreservation of oocytes (19%) or ovarian tissue (13%) for postponing fertility or menopause was generally low, but increased (37%) if both goals could be achieved with one surgery. Cryopreservation of ovarian tissue for postponing menopause was acceptable for 22% of women. Not having a suitable partner until age 35 increased the likelihood of considering postponing fertility by cryopreservation (p < 0.001) and had a stronger impact on that decision than the factor "pursuing a career" (p < 0.001). CONCLUSION: More education on age-related fertility decline, menopause and HT (benefit-risk ratio) is needed. Furthermore, the political and socioeconomic discussion should focus on women's needs, especially on compatibility of career and family.
PURPOSE: To assess the attitude towards ovarian tissue and oocyte cryopreservation for non-medical reasons. METHODS: Cross-sectional electronic survey in 248 Swiss women aged 15-35 years, nationally representative for educational level. RESULTS: Most women did not worry about an age-related fertility decline. Two-thirds of women would consider using hormone therapy (HT) for menopausal symptom relief although concerns about side effects and risks were still high. Acceptance of cryopreservation of oocytes (19%) or ovarian tissue (13%) for postponing fertility or menopause was generally low, but increased (37%) if both goals could be achieved with one surgery. Cryopreservation of ovarian tissue for postponing menopause was acceptable for 22% of women. Not having a suitable partner until age 35 increased the likelihood of considering postponing fertility by cryopreservation (p < 0.001) and had a stronger impact on that decision than the factor "pursuing a career" (p < 0.001). CONCLUSION: More education on age-related fertility decline, menopause and HT (benefit-risk ratio) is needed. Furthermore, the political and socioeconomic discussion should focus on women's needs, especially on compatibility of career and family.