Literature DB >> 29699126

Toward standardization of the cut-off value for the direct immunobead test using the postcoital test in immunologically infertile males.

Junko Koriyama1, Hiroaki Shibahara1, Tomoe Ikeda1, Yuki Hirano1, Tatsuya Suzuki1, Mitsuaki Suzuki1.   

Abstract

PURPOSE: There is a need to improve our understanding of the cut-off value of the direct immunobead test (D-IBT).
METHODS: The subjects were 26 D-IBT-positive and 140 D-IBT-negative males. The results of post coital tests (PCTs) for each subject were examined.
RESULTS: A significant difference was observed in abnormal PCTs between values <20 % and those ≥20 % (P = 0.02). However, there was no significant difference in abnormal PCTs between values <50 % and those ≥50 % (P = 0.084).
CONCLUSIONS: A cut-off value of 20 % was correlated with the possibility of conception on treatment with IUI. The D-IBT is a screening test, and the value of 20 % initially suggested by Bronson et al. seems to be more appropriate than that of 50 % in the criteria defined by the World Health Organization.

Entities:  

Keywords:  Antisperm antibody; Cut‐off value; Direct immunobead test; Male infertility; Postcoital test

Year:  2012        PMID: 29699126      PMCID: PMC5904582          DOI: 10.1007/s12522-012-0135-8

Source DB:  PubMed          Journal:  Reprod Med Biol        ISSN: 1445-5781


  14 in total

1.  The hemizona assay (HZA): development of a diagnostic test for the binding of human spermatozoa to the human hemizona pellucida to predict fertilization potential.

Authors:  L J Burkman; C C Coddington; D R Franken; T F Krugen; Z Rosenwaks; G D Hogen
Journal:  Fertil Steril       Date:  1988-04       Impact factor: 7.329

2.  Anti-sperm antibody levels are not related to fertilization or pregnancy rates after IVF or IVF/ICSI.

Authors:  Armand Zini; Josee Lefebvre; Gaelle Kornitzer; Francois Bissonnette; Isaac Jacques Kadoch; Nicola Dean; Simon Phillips
Journal:  J Reprod Immunol       Date:  2010-12-15       Impact factor: 4.054

3.  Diversity of the blocking effects of antisperm antibodies on fertilization in human and mouse.

Authors:  H Shibahara; M Shigeta; M Inoue; A Hasegawa; K Koyama; N J Alexander; S Isojima
Journal:  Hum Reprod       Date:  1996-12       Impact factor: 6.918

4.  Human sperm proteome: immunodominant sperm surface antigens identified with sera from infertile men and women.

Authors:  J Shetty; S Naaby-Hansen; H Shibahara; R Bronson; C J Flickinger; J C Herr
Journal:  Biol Reprod       Date:  1999-07       Impact factor: 4.285

5.  Diversity of the inhibitory effects on fertilization by anti-sperm antibodies bound to the surface of ejaculated human sperm.

Authors:  Hiroaki Shibahara; Yasuko Shiraishi; Yuki Hirano; Tatsuya Suzuki; Satoru Takamizawa; Mitsuaki Suzuki
Journal:  Hum Reprod       Date:  2003-07       Impact factor: 6.918

6.  Sperm immobilizing antibodies interfere with sperm migration from the uterine cavity through the fallopian tubes.

Authors:  H Shibahara; M Shigeta; H Toji; K Koyama
Journal:  Am J Reprod Immunol       Date:  1995-08       Impact factor: 3.886

7.  Treatment of antibody-associated sperm with media containing high serum content: a prospective trial of fertility involving men with high antisperm antibodies following intrauterine insemination.

Authors:  W Byrd; W H Kutteh; B R Carr
Journal:  Am J Reprod Immunol       Date:  1994 Mar-Apr       Impact factor: 3.886

8.  Effects of sperm-immobilizing antibodies on sperm-zona pellucida tight binding.

Authors:  H Shibahara; L J Burkman; S Isojima; N J Alexander
Journal:  Fertil Steril       Date:  1993-09       Impact factor: 7.329

Review 9.  Diagnosis and treatment of immunologically infertile males with antisperm antibodies.

Authors:  Hiroaki Shibahara; Yasuko Shiraishi; Mitsuaki Suzuki
Journal:  Reprod Med Biol       Date:  2005-05-03

10.  Ability of antibody-bound human sperm to penetrate zona-free hamster ova in vitro.

Authors:  R Bronson; G Cooper; D Rosenfeld
Journal:  Fertil Steril       Date:  1981-12       Impact factor: 7.329

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