Literature DB >> 29698965

Lack of Change in the Adaptation Ability of the Bladder for the Urine Production Rate in Aged Men with Nocturia.

Satoru Kira, Takahiko Mitsui, Tatsuya Miyamoto, Tatsuya Ihara, Hiroshi Nakagomi, Norifumi Sawada, Masayuki Takeda.   

Abstract

INTRODUCTION: To investigate the association between bladder capacity and the urine production rate in aged men with or without nocturia using a frequency volume chart (FVC).
MATERIALS AND METHODS: One-hundred and thirty-eight men aged 65-80 years were enrolled. After the International Prostate Symptom Score (IPSS) and 3 consecutive days FVC were evaluated, men were divided into 2 groups: Nocturia group, with any total IPSS, and ≥1.5 micturition on average at night; and Control group, with total IPSS < 8 and < 1.5 micturition on average at night. Each parameter was compared between the 2 groups using unpaired t tests. Linear and multiple regression analyses were performed between the urine production rate and volume/voids.
RESULTS: Men numbering 45 and 21 were assigned to the Nocturia and Control groups respectively. There were no differences in background factors between the 2 groups. Volume/voids positively correlated with the urine production rate in both groups for day and night. A multivariate regression model also showed the same results. In the Control group, the degree of slope at night was higher than that during the day. However, in the Nocturia group, there were no differences in the degree of slope between day and night.
CONCLUSIONS: This novel finding has led to a possibility for resolving nocturia.
© 2018 S. Karger AG, Basel.

Entities:  

Keywords:  Aged men; Bladder capacity; Frequency volume chart; Nocturia; Urine production rate

Mesh:

Year:  2018        PMID: 29698965     DOI: 10.1159/000488002

Source DB:  PubMed          Journal:  Urol Int        ISSN: 0042-1138            Impact factor:   2.089


  4 in total

1.  Urinary metabolites identified using metabolomic analysis as potential biomarkers of nocturia in elderly men.

Authors:  Satoru Kira; Takahiko Mitsui; Tatsuya Miyamoto; Tatsuya Ihara; Hiroshi Nakagomi; Yuka Hashimoto; Hajime Takamatsu; Masayuki Tanahashi; Masahiro Takeda; Sachiko Tsuchiya; Norifumi Sawada; Masayuki Takeda
Journal:  World J Urol       Date:  2019-12-03       Impact factor: 4.226

2.  Metabolomics analysis of blood identifies potential biomarkers and possible treatment targets for nocturia.

Authors:  Satoru Kira; Takahiko Mitsui; Tatsuya Miyamoto; Tatsuya Ihara; Hiroshi Nakagomi; Yuka Hashimoto; Hajime Takamatsu; Masayuki Tanahashi; Masahiro Takeda; Norifumi Sawada; Masayuki Takeda
Journal:  Ther Adv Urol       Date:  2019-05-17

3.  Intermittent restraint stress induces circadian misalignment in the mouse bladder, leading to nocturia.

Authors:  Tatsuya Ihara; Yuki Nakamura; Takahiko Mitsui; Sachiko Tsuchiya; Mie Kanda; Satoru Kira; Hiroshi Nakagomi; Norifumi Sawada; Manabu Kamiyama; Eiji Shigetomi; Youichi Shinozaki; Mitsuharu Yoshiyama; Atsuhito Nakao; Schuichi Koizumi; Masayuki Takeda
Journal:  Sci Rep       Date:  2019-07-11       Impact factor: 4.379

4.  Effects of fatty acid metabolites on nocturia.

Authors:  Tatsuya Ihara; Hiroshi Shimura; Sachiko Tsuchiya; Mie Kanda; Satoru Kira; Norifumi Sawada; Masayuki Takeda; Takahiko Mitsui; Eiji Shigetomi; Yoichi Shinozaki; Schuichi Koizumi
Journal:  Sci Rep       Date:  2022-02-23       Impact factor: 4.379

  4 in total

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