Soraya Azmi1, Adrian Goh2, Alan Fong3, Lawrence Anchah4. 1. Azmi Burhani Consulting, Petaling Jaya, Malaysia; Veras Research, Petaling Jaya, Malaysia. Electronic address: soraya.azmi@azmi-burhani.com. 2. Azmi Burhani Consulting, Petaling Jaya, Malaysia; Veras Research, Petaling Jaya, Malaysia. 3. Sarawak General Hospital Heart Centre, Sarawak, Malaysia; Clinical Research Centre, Sarawak General Hospital, Sarawak, Malaysia; Faculty of Medicine and Health Sciences, Universiti Malaysia, Sarawak, Malaysia. 4. Sarawak General Hospital Heart Centre, Sarawak, Malaysia.
Abstract
OBJECTIVES: This study's objectives were to estimate the quality of life (QOL) of Malaysian patients with acute coronary syndrome (ACS) during admission and at 12 months, to explore the factors associated with the QOL, and to compare utility scores derived from tariffs from local and foreign populations. METHODS: Data collected from patients with ACS between 2008 and 2009 for a study on cardiac rehabilitation at the Sarawak General Hospital were used for this study. QOL data were obtained using a validated version of the EuroQol five-dimensional questionnaire at baseline and at 12 months. Health utility scores were calculated using visual analogue scale scores and utility tariffs from Malaysia and the United Kingdom. RESULTS: Data from 104 subjects from the earlier study was used. The mean age was 56.1 years, with 88.5% being men. The mean hospitalization duration was 6.3 days. The mean utility score was 0.75 at baseline and 0.82 at 12 months. There was a statistically significant improvement in utility from baseline to 12 months based on the Malaysian tariff (P = 0.014) but not with the UK tariff (P = 0.086). The QOL of patients was associated with sex and diagnosis of ST-segment elevation myocardial infarction. CONCLUSIONS: Our results showed that there was a significant improvement in the QOL from baseline to 12 months. Only sex and diagnosis affected the QOL score at baseline because of limited variables available for testing. It also reconfirms the importance of applying the appropriate, country-specific utility tariffs in QOL studies. Despite limitations, the study is useful toward describing QOL among a group of Malaysian patients with ACS.
OBJECTIVES: This study's objectives were to estimate the quality of life (QOL) of Malaysian patients with acute coronary syndrome (ACS) during admission and at 12 months, to explore the factors associated with the QOL, and to compare utility scores derived from tariffs from local and foreign populations. METHODS: Data collected from patients with ACS between 2008 and 2009 for a study on cardiac rehabilitation at the Sarawak General Hospital were used for this study. QOL data were obtained using a validated version of the EuroQol five-dimensional questionnaire at baseline and at 12 months. Health utility scores were calculated using visual analogue scale scores and utility tariffs from Malaysia and the United Kingdom. RESULTS: Data from 104 subjects from the earlier study was used. The mean age was 56.1 years, with 88.5% being men. The mean hospitalization duration was 6.3 days. The mean utility score was 0.75 at baseline and 0.82 at 12 months. There was a statistically significant improvement in utility from baseline to 12 months based on the Malaysian tariff (P = 0.014) but not with the UK tariff (P = 0.086). The QOL of patients was associated with sex and diagnosis of ST-segment elevation myocardial infarction. CONCLUSIONS: Our results showed that there was a significant improvement in the QOL from baseline to 12 months. Only sex and diagnosis affected the QOL score at baseline because of limited variables available for testing. It also reconfirms the importance of applying the appropriate, country-specific utility tariffs in QOL studies. Despite limitations, the study is useful toward describing QOL among a group of Malaysian patients with ACS.
Authors: Liqaa A Raffee; Khaled Z Alawneh; Mohammad Khaled Al Suleiman; Rashid K Ibdah; Sukaina I Rawashdeh; Abdel-Hameed W Al-Mistarehi Journal: Ann Med Surg (Lond) Date: 2020-10-02
Authors: Robin Hofmann; Tamrat Befekadu Abebe; Johan Herlitz; Stefan K James; David Erlinge; Troels Yndigegn; Joakim Alfredsson; Thomas Kellerth; Annica Ravn-Fischer; Sebastian Völz; Jörg Lauermann; Tomas Jernberg; Bertil Lindahl; Sophie Langenskiöld Journal: Front Cardiovasc Med Date: 2021-03-15
Authors: Billingsley Kaambwa; Hailay Abrha Gesesew; Matthew Horsfall; Derek Chew Journal: Int J Environ Res Public Health Date: 2020-09-21 Impact factor: 3.390
Authors: Bach Xuan Tran; Mackenzie Pi Moir; Thao Phuong Thi Thai; Long Hoang Nguyen; Giang Hai Ha; Thu Hong Thi Nguyen; Nu Thi Truong; Carl A Latkin Journal: Biomed Res Int Date: 2018-09-26 Impact factor: 3.411