Franziska Rudzik1,2, Laurie Thiesse1,2, Reto Pieren3, Jean Marc Wunderli3, Mark Brink4, Maria Foraster5,6, Harris Héritier5,6, Ikenna C Eze5,6, Corrado Garbazza1,2, Danielle Vienneau5,6, Nicole Probst-Hensch5,6, Martin Röösli5,6, Christian Cajochen1,2. 1. Centre for Chronobiology, Psychiatric Hospital of the University of Basel, Basel, Switzerland. 2. Transfaculty Research Platform Molecular and Cognitive Neurosciences, University of Basel, Basel, Switzerland. 3. Empa, Laboratory for Acoustics/Noise Control, Swiss Federal Laboratories for Materials Science and Technology, Dübendorf, Switzerland. 4. Department of Noise and Non-ionizing Radiation, Federal Office for the Environment, Bern, Switzerland. 5. Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland. 6. University of Basel, Basel, Switzerland.
Abstract
Study Objectives: Nighttime transportation noise elicits awakenings, sleep-stage changes, and electroencephalographic (EEG) arousals. Here, we investigated the potential sleep-protective role of sleep spindles on noise-induced sleep alterations. Methods: Twenty-six young (19-33 years, 12 women) and 18 older (52-70 years, 9 women) healthy volunteers underwent a repeated measures polysomnographic 6-day laboratory study. Participants spent one noise-free baseline night, followed by four transportation noise-exposure nights (road traffic or railway noise; continuous or intermittent: average sound levels of 45 dB, maximum sound levels of 50-62 dB), and one noise-free recovery night. Sleep stages were scored manually and fast sleep spindle characteristics were quantified automatically using an individual band-pass filtering approach. Results: Nighttime exposure to transportation noise significantly increased sleep EEG arousal indices. Sleep structure and continuity were not differentially affected by noise exposure in individuals with a low versus a high spindle rate. Spindle rates showed an age-related decline along with more noise-induced sleep alterations. All-night spindle rates did not predict EEG arousal or awakening probability from single railway noise events. Spindle characteristics were affected in noise-exposure nights compared to noise-free nights: we observed a reduction of the spindle amplitude in both age groups and of the spindle rate in the older group. Conclusions: We have evidence that spindle rate is more likely to represent a trait phenomenon, which does not seem to play a sleep-protective role in nighttime transportation noise-induced sleep disruptions. However, the marked reduction in spindle amplitude is most likely a sensitive index for noise-induced sleep alterations.
Study Objectives: Nighttime transportation noise elicits awakenings, sleep-stage changes, and electroencephalographic (EEG) arousals. Here, we investigated the potential sleep-protective role of sleep spindles on noise-induced sleep alterations. Methods: Twenty-six young (19-33 years, 12 women) and 18 older (52-70 years, 9 women) healthy volunteers underwent a repeated measures polysomnographic 6-day laboratory study. Participants spent one noise-free baseline night, followed by four transportation noise-exposure nights (road traffic or railway noise; continuous or intermittent: average sound levels of 45 dB, maximum sound levels of 50-62 dB), and one noise-free recovery night. Sleep stages were scored manually and fast sleep spindle characteristics were quantified automatically using an individual band-pass filtering approach. Results: Nighttime exposure to transportation noise significantly increased sleep EEG arousal indices. Sleep structure and continuity were not differentially affected by noise exposure in individuals with a low versus a high spindle rate. Spindle rates showed an age-related decline along with more noise-induced sleep alterations. All-night spindle rates did not predict EEG arousal or awakening probability from single railway noise events. Spindle characteristics were affected in noise-exposure nights compared to noise-free nights: we observed a reduction of the spindle amplitude in both age groups and of the spindle rate in the older group. Conclusions: We have evidence that spindle rate is more likely to represent a trait phenomenon, which does not seem to play a sleep-protective role in nighttime transportation noise-induced sleep disruptions. However, the marked reduction in spindle amplitude is most likely a sensitive index for noise-induced sleep alterations.
Authors: Julia Carbone; Carlos Bibián; Patrick Reischl; Jan Born; Cecilia Forcato; Susanne Diekelmann Journal: Learn Mem Date: 2021-08-16 Impact factor: 2.699
Authors: Martin Röösli; Mark Brink; Franziska Rudzik; Christian Cajochen; Martina S Ragettli; Benjamin Flückiger; Reto Pieren; Danielle Vienneau; Jean-Marc Wunderli Journal: Int J Environ Res Public Health Date: 2019-10-09 Impact factor: 3.390
Authors: Daphne O Chylinski; Maxime Van Egroo; Justinas Narbutas; Martin Grignard; Ekaterina Koshmanova; Christian Berthomier; Pierre Berthomier; Marie Brandewinder; Eric Salmon; Mohamed Ali Bahri; Christine Bastin; Fabienne Collette; Christophe Phillips; Pierre Maquet; Vincenzo Muto; Gilles Vandewalle Journal: JCI Insight Date: 2021-12-22
Authors: Mark Brink; Beat Schäffer; Danielle Vienneau; Reto Pieren; Maria Foraster; Ikenna C Eze; Franziska Rudzik; Laurie Thiesse; Christian Cajochen; Nicole Probst-Hensch; Martin Röösli; Jean Marc Wunderli Journal: Int J Environ Res Public Health Date: 2019-10-29 Impact factor: 3.390