| Literature DB >> 2969695 |
J de Grouchy1, A Nicole, C Cochet, N Créau-Goldberg, P M Sinet.
Abstract
A twofold CuZnSOD activity was observed in an orangutan as compared to man and a chimpanzee. This suggests that a submicroscopic duplication of chromosome 21 (similar to those demonstrated in patients with the trisomy 21 phenotype but with a normal karyotype) has occurred in the homozygous state during evolution of the orangutan phylum. Such duplications could be important evolutionary mechanisms, together with visible chromosome rearrangements and classical gene mutations.Entities:
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Year: 1988 PMID： 2969695
Source DB: PubMed Journal: Ann Genet ISSN： 0003-3995