Literature DB >> 29695453

Fundamental science behind today's important medicines.

Jonathan M Spector1, Rosemary S Harrison1, Mark C Fishman2.   

Abstract

Today's most transformative medicines exist because of fundamental discoveries that were made without regard to practical outcome and with their relevance to therapeutics only appearing decades later.
Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Mesh：

Year:  2018        PMID： 29695453     DOI： 10.1126/scitranslmed.aaq1787

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN： 1946-6234            Impact factor:   17.956


  8 in total

1.  Academia and industry: allocating credit for discovery and development of new therapies.

Authors:  Jeffrey S Flier
Journal:  J Clin Invest       Date:  2019-05-20       Impact factor: 14.808

Review 2.  Migraine and the trigeminovascular system-40 years and counting.

Authors:  Messoud Ashina; Jakob Møller Hansen; Thien Phu Do; Agustin Melo-Carrillo; Rami Burstein; Michael A Moskowitz
Journal:  Lancet Neurol       Date:  2019-05-31       Impact factor: 44.182

3.  The NIH Open Citation Collection: A public access, broad coverage resource.

Authors:  B Ian Hutchins; Kirk L Baker; Matthew T Davis; Mario A Diwersy; Ehsanul Haque; Robert M Harriman; Travis A Hoppe; Stephen A Leicht; Payam Meyer; George M Santangelo
Journal:  PLoS Biol       Date:  2019-10-10       Impact factor: 8.029

4.  Predicting translational progress in biomedical research.

Authors:  B Ian Hutchins; Matthew T Davis; Rebecca A Meseroll; George M Santangelo
Journal:  PLoS Biol       Date:  2019-10-10       Impact factor: 8.029

5.  Public sector financial support for late stage discovery of new drugs in the United States: cohort study.

Authors:  Rahul K Nayak; Jerry Avorn; Aaron S Kesselheim
Journal:  BMJ       Date:  2019-10-23

6.  The rise to dominance of genetic model organisms and the decline of curiosity-driven organismal research.

Authors:  Sarah M Farris
Journal:  PLoS One       Date:  2020-12-01       Impact factor: 3.240

Review 7.  High Fidelity of Mouse Models Mimicking Human Genetic Skeletal Disorders.

Authors:  Robert Brommage; Claes Ohlsson
Journal:  Front Endocrinol (Lausanne)       Date:  2020-02-04       Impact factor: 5.555

8.  Public research funding and pharmaceutical prices: do Americans pay twice for drugs?

Authors:  Rena M Conti; Frank S David
Journal:  F1000Res       Date:  2020-07-15
  8 in total

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