Literature DB >> 29695000

New Diagnostic Possibilities for Neonatal Sepsis.

Chryssoula Tzialla1, Paolo Manzoni2, Cristian Achille1, Lina Bollani1, Mauro Stronati1, Alessandro Borghesi1.   

Abstract

Progress in neonatal care has decrease morbidity and mortality due to neonatal sepsis (NS). Although diagnosis of sepsis continues to rely on blood culture, this method is too slow and limited by false-negative results. There are numerous sepsis biomarkers that have been evaluated for the early diagnosis of NS, but, to date, there is no single ideal biomarker, though novel biomarkers are becoming more sophisticated and specific in their clinical applications. This review provides an overview of the current diagnostic approaches available or under development for diagnosing NS. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

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Year:  2018        PMID: 29695000     DOI: 10.1055/s-0038-1639361

Source DB:  PubMed          Journal:  Am J Perinatol        ISSN: 0735-1631            Impact factor:   1.862


  8 in total

Review 1.  Proadrenomedullin and neonatal sepsis: a systematic review and meta-analysis of diagnostic accuracy.

Authors:  Gerasimos Panagiotis Milas; Vasileios Issaris
Journal:  Eur J Pediatr       Date:  2021-08-03       Impact factor: 3.183

2.  miR-141 is negatively correlated with TLR4 in neonatal sepsis and regulates LPS-induced inflammatory responses in monocytes.

Authors:  Xinyu Lin; Yaohui Wang
Journal:  Braz J Med Biol Res       Date:  2021-05-17       Impact factor: 2.590

Review 3.  Relevance of Biomarkers Currently in Use or Research for Practical Diagnosis Approach of Neonatal Early-Onset Sepsis.

Authors:  Maura-Adelina Hincu; Gabriela-Ildiko Zonda; Gabriela Dumitrita Stanciu; Dragos Nemescu; Luminita Paduraru
Journal:  Children (Basel)       Date:  2020-12-20

4.  Downregulation of miR-1184 serves as a diagnostic biomarker in neonatal sepsis and regulates LPS-induced inflammatory response by inhibiting IL-16 in monocytes.

Authors:  Dan Wang; Lina Han
Journal:  Exp Ther Med       Date:  2021-02-11       Impact factor: 2.447

5.  The potential value of plasma receptor interacting protein 3 in neonates with culture-positive late-onset sepsis.

Authors:  Chuchu Gao; Zongtai Feng; Lixia Wang; Xingxing Zhao; Kai Fu; Shurong Ma; Zuming Yang; Sannan Wang; Shenglin Yu
Journal:  BMC Infect Dis       Date:  2021-09-06       Impact factor: 3.090

Review 6.  Predictive Scores for Late-Onset Neonatal Sepsis as an Early Diagnostic and Antimicrobial Stewardship Tool: What Have We Done So Far?

Authors:  Georgia Anna Sofouli; Aimilia Kanellopoulou; Aggeliki Vervenioti; Gabriel Dimitriou; Despoina Gkentzi
Journal:  Antibiotics (Basel)       Date:  2022-07-10

7.  BCL-xL is correlated with disease severity in neonatal infants with early sepsis.

Authors:  Wu Wenshen; Peng Qi; Huang Tianli; Liao Jinfeng; Li Ning
Journal:  BMC Pediatr       Date:  2021-06-30       Impact factor: 2.125

8.  Neonatal blood culture inoculant volume: feasibility and challenges.

Authors:  Emily C Woodford; Miren B Dhudasia; Karen M Puopolo; Lauren A Skerritt; Meera Bhavsar; Joanne DeLuca; Sagori Mukhopadhyay
Journal:  Pediatr Res       Date:  2021-04-06       Impact factor: 3.756

  8 in total

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