Literature DB >> 29693414

2-Methyl-versiquinazoline C, a new fumiquinazoline-type alkaloid from the fungus Aspergillus flavipes PJ03-11.

Ying-Ying Si1,2, Ming-Xu Tang1,2, Shuang Lin1,2, Gang Chen1,2, Hui-Ming Hua1,2, Jiao Bai1,2, Yu-Bo Wang1,2,3, Hai-Feng Wang1,2, Yue-Hu Pei1,2.   

Abstract

A new fumiquinazoline-type alkaloid 2-methyl-versiquinazoline C (1), together with six known compounds (2-7), was isolated from Aspergillus flavipes PJ03-11 using OSMAC method. Their structures were elucidated on the basis of extensive spectroscopic analysis, and the absolute configuration of compound 1 was determined by the experimental and calculated ECD data. In addition, the cytotoxic activities against three human cancer cell lines (HL-60, THP-1, and PC-3) were evaluated.

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Keywords:  ; OSMAC; fumiquinazoline-type alkaloid

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Year:  2018        PMID: 29693414     DOI: 10.1080/10286020.2018.1463999

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  1 in total

1.  Neuroinflammatory inhibitors from Gardneria nutans Siebold & Zuccarini.

Authors:  Ying-Ying Si; Wei-Wei Wang; Qing-Mei Feng; Zhen-Zhu Zhao; Gui-Min Xue; Yan-Jun Sun; Wei-Sheng Feng; Jun-Im Young; Xian-Shi Wang
Journal:  RSC Adv       Date:  2021-08-09       Impact factor: 4.036

  1 in total

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