Literature DB >> 29691687

[Characteristics of pharmacotherapy in older patients with rheumatism].

H-J Lakomek1, Christian Schulz2.   

Abstract

Due to medical advances and the availability of efficient immunosuppressive therapies, the life-expectancy of people suffering from inflammatory rheumatic diseases is continuously increasing. In Germany, geriatric patients (definition: age older than 70 years combined with geriatric multimorbidity) affected, e. g. by rheumatoid arthritis (RA) frequently receive corticosteroids and less often biologic disease-modifying antirheumatic drugs (bDMARDs) and conventional DMARDs (cDMARDs), which is justified by additionally existing comorbidities and polypharmacy. Using geriatric typical assessments as well as detailed medication regimens the treatment risk of bDMARD and cDMARD administration can be properly evaluated. Current data on biological therapy in older patients with rheumatism support this recommendation. Following the "choosing wisely" initiative of the German Association of Internal Medicine the authors listed 5 positive and 5 negative recommendations concerning the pharmacotherapy of older patients suffering from rheumatism (e. g. RA) as practical guidance towards safer bDMARD and cDMARD treatment for geriatric RA patients.

Entities:  

Keywords:  Biologics; Geriatric patient; Geriatric syndromes; Multimorbidity; Treatment risk

Mesh:

Substances:

Year:  2018        PMID: 29691687     DOI: 10.1007/s00393-018-0460-3

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN: 0340-1855            Impact factor:   1.372


  40 in total

1.  The Timed Test of Money Counting: a short physical performance test for manual dexterity and cognitive capacity.

Authors:  T Nikolaus; M Bach; N Specht-Leible; P Oster; G Schlierf
Journal:  Age Ageing       Date:  1995-05       Impact factor: 10.668

Review 2.  [Choosing wisely recommendations in rheumatology : One year after their first publication].

Authors:  E Märker-Hermann; A J Voormann
Journal:  Internist (Berl)       Date:  2017-06       Impact factor: 0.743

3.  Geriatricians: The Super Specialists.

Authors:  John E Morley
Journal:  J Am Geriatr Soc       Date:  2017-02-08       Impact factor: 5.562

Review 4.  Exercise as an anti-inflammatory therapy for rheumatic diseases-myokine regulation.

Authors:  Fabiana B Benatti; Bente K Pedersen
Journal:  Nat Rev Rheumatol       Date:  2014-11-25       Impact factor: 20.543

Review 5.  Consensus statement on a framework for the management of comorbidity and extra-articular manifestations in rheumatoid arthritis.

Authors:  Estíbaliz Loza; Cristina Lajas; Jose Luis Andreu; Alejandro Balsa; Isidoro González-Álvaro; Oscar Illera; Juan Ángel Jover; Isabel Mateo; Javier Orte; Javier Rivera; José Manuel Rodríguez Heredia; Fredeswinda Romero; Juan Antonio Martínez-López; Ana María Ortiz; Esther Toledano; Virginia Villaverde; Loreto Carmona; Santos Castañeda
Journal:  Rheumatol Int       Date:  2014-12-28       Impact factor: 2.631

6.  Potentially inappropriate medications in the elderly: the PRISCUS list.

Authors:  Stefanie Holt; Sven Schmiedl; Petra A Thürmann
Journal:  Dtsch Arztebl Int       Date:  2010-08-09       Impact factor: 5.594

7.  [Which kind of structures and facilities are needed for the care of elderly patients with rheumatic diseases?].

Authors:  C Fiehn
Journal:  Z Rheumatol       Date:  2014-04       Impact factor: 1.372

8.  Clinical presentation, burden of disease and treatment in young-onset and late-onset rheumatoid arthritis: a matched-pairs analysis taking age and disease duration into account.

Authors:  Dörte Huscher; Claudia Sengler; Erika Gromnica-Ihle; Sascha Bischoff; Thorsten Eidner; Wolfgang Ochs; Jutta Richter; Angela Zink
Journal:  Clin Exp Rheumatol       Date:  2013-01-09       Impact factor: 4.473

9.  Relationship between exposure to tumour necrosis factor inhibitor therapy and incidence and severity of myocardial infarction in patients with rheumatoid arthritis.

Authors:  Audrey S L Low; Deborah P M Symmons; Mark Lunt; Louise K Mercer; Chris P Gale; Kath D Watson; William G Dixon; Kimme L Hyrich
Journal:  Ann Rheum Dis       Date:  2017-01-10       Impact factor: 19.103

10.  Comparing clinician descriptions of frailty and geriatric syndromes using electronic health records: a retrospective cohort study.

Authors:  Laura J Anzaldi; Ashwini Davison; Cynthia M Boyd; Bruce Leff; Hadi Kharrazi
Journal:  BMC Geriatr       Date:  2017-10-25       Impact factor: 3.921

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  1 in total

1.  [Therapeutic effects of complex multimodal rheumatologic treatment in the Rheumatology Center, Rhineland-Palatinate].

Authors:  K Triantafyllias; C Sauer; A Schwarting
Journal:  Z Rheumatol       Date:  2022-05-09       Impact factor: 1.530

  1 in total

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