R Grobholz1,2. 1. Institut für Pathologie, Kantonsspital Aarau, Tellstrasse 25, 5001, Aarau, Schweiz. Rainer.Grobholz@ksa.ch. 2. Medizinische Fakultät, Universität Zürich, Zürich, Schweiz. Rainer.Grobholz@ksa.ch.
Abstract
BACKGROUND: Digital pathology (DP) and whole-slide imaging (WSI) technology have matured substantially over the last few years. Meanwhile, commercial systems are available that can be used in routine practice. AIMS: Illustration of DP experiences in a routine diagnostic setting. RESULTS AND CONCLUSIONS: A DP system offers several advantages: 1) glass slides are no longer unique; 2) access to cases is possible from any location; 3) digital image analysis can be applied; and 4) archived WSI can be easily accessed. From this point, several secondary advantages arise: a) the slide compilation of the case and the case assignment is fast and safe; b) carrying cases to the pathologist is obsolete and paperless work is possible; c) WSI can be used for a second opinion and be accessible in remote locations; d) WSI of referred cases are still accessible after returning the slides; e) histological images can easily be provided in tumor boards; f) the office desk is clean; and g) a "home office" is possible. To introduce a DP system, a comprehensive workflow analysis is needed that clarifies the needs and wishes of the respective institute. In order to optimally meet the requirements, open DP platforms are of particular advantage, because they enable the integration of scanners from various manufacturers. Further developments in image analysis, such as virtual tissue reconstruction, could enrich the diagnostic process in the future and improve treatment quality.
BACKGROUND: Digital pathology (DP) and whole-slide imaging (WSI) technology have matured substantially over the last few years. Meanwhile, commercial systems are available that can be used in routine practice. AIMS: Illustration of DP experiences in a routine diagnostic setting. RESULTS AND CONCLUSIONS: A DP system offers several advantages: 1) glass slides are no longer unique; 2) access to cases is possible from any location; 3) digital image analysis can be applied; and 4) archived WSI can be easily accessed. From this point, several secondary advantages arise: a) the slide compilation of the case and the case assignment is fast and safe; b) carrying cases to the pathologist is obsolete and paperless work is possible; c) WSI can be used for a second opinion and be accessible in remote locations; d) WSI of referred cases are still accessible after returning the slides; e) histological images can easily be provided in tumor boards; f) the office desk is clean; and g) a "home office" is possible. To introduce a DP system, a comprehensive workflow analysis is needed that clarifies the needs and wishes of the respective institute. In order to optimally meet the requirements, open DP platforms are of particular advantage, because they enable the integration of scanners from various manufacturers. Further developments in image analysis, such as virtual tissue reconstruction, could enrich the diagnostic process in the future and improve treatment quality.
Entities:
Keywords:
Automatic data processing; Computer-assisted image interpretation; Informatics; Pathology; Workflow
Authors: Liron Pantanowitz; John H Sinard; Walter H Henricks; Lisa A Fatheree; Alexis B Carter; Lydia Contis; Bruce A Beckwith; Andrew J Evans; Avtar Lal; Anil V Parwani Journal: Arch Pathol Lab Med Date: 2013-05-01 Impact factor: 5.534