| Literature DB >> 29689225 |
Rajesh Ramachandran1, Sandra L Schmid2.
Abstract
The dynamin superfamily comprises a growing assortment of multi-domain GTPases, found from bacteria to man, that are distinguished from typical GTPases of the Ras, Rab and G-protein families by their modular structure (Figure 1), relatively large size (>70 kDa), and low affinity for guanine nucleotides. In addition, they display a conserved propensity to self-assemble into polymeric arrays, the dynamics of which are regulated by an autonomous, assembly-stimulated GTPase activity.Entities:
Mesh：
Substances：
Year: 2018 PMID： 29689225 DOI： 10.1016/j.cub.2017.12.013
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834