Influence of electronic cigarettes puffing regimes on amount of vaporized liquid.

E-cigarette (EC) was designed to provide less harmful alternative to conventional cigarettes. Along with growing popularity of ECs around the world, more products have appeared on the market. There are limited safety studies and data relating to potential toxicity of EC use. Therefore, there is strong need to gain thorough information about a composition of generated aerosol from ECs. Due to the fact that ECs settings and puffing regimes influence vapor and toxins generation, we decided to identify parameters that have the greatest impact on the aerosol yield. Material and
Methods: We took into account three puffing parameters: puff volume, puff duration and interpuff interval. The study was divided into two stages. In a first stage puffing regimes were achieved in testing volunteers (14 men and 11 women). In a second one found parameters (volume, puffs durations, intervals between puffs) were used to mimic ECs use in laboratory settings to examine influence of different puffing regimes on aerosol yields. Smoking machine was used to generate aerosol (6 times for each set of parameters). Aerosol yield was represented as amount of e-liquid trapped on Cambridge filter.
Results: The results of puffing regimes study among ECs users are presented as mean ± SD: puff volume [mL] 65 ± 49, puff duration [s] 2.8 ± 2.7 and intervals between puffs [s] 16 ± 40. Aerosol yields varied depending on the set puffing regimes. Conclusions: Our results indicate that the most important puffing parameters, which determine aerosol yield, are puffs duration and interpuff intervals. Puffs volume (between 41- 76 mL) has no influence on aerosol yield.