| Literature DB >> 29688554 |
Rebecca Zash1,2,3, Kathryn Rough4,5, Denise L Jacobson6, Modiegi Diseko3, Gloria Mayondi3, Mompati Mmalane3, Max Essex2,3, Chipo Petlo7, Shahin Lockman2,3,8, Joseph Makhema3, Roger L Shapiro2,3.
Abstract
Among human immunodeficiency virus-positive women in Botswana on the recommended first-line antiretroviral therapy regimen, tenofovir-emtricitabine-efavirenz, initiated within the first or early second trimester, we found no increased risk of stillbirth, neonatal death, preterm/very preterm delivery, or the infant being born small or very small for gestational age. Treatment with tenofovir-emtricitabine-efavirenz <1 year before conception increased the risk of preterm delivery slightly over late-second-trimester treatment initiation (adjusted risk ratio, 1.33 [95% confidence interval, 1.04-1.70]).Entities:
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Year: 2018 PMID: 29688554 PMCID: PMC6097579 DOI: 10.1093/jpids/piy006
Source DB: PubMed Journal: J Pediatric Infect Dis Soc ISSN: 2048-7193 Impact factor: 3.164