Literature DB >> 29687379

Differentiation of Brown Adipocyte Progenitors Derived from Human Induced Pluripotent Stem Cells.

Anne-Laure Hafner1, Tala Mohsen-Kanson1,2, Christian Dani3.   

Abstract

In this chapter, we describe a protocol to induce at a high rate the differentiation of brown/brown like adipocyte progenitors (BAPs) derived from human induced pluripotent stem cells (hiPSCs). We also describe culture conditions to maintain hiPSCs and to derive hiPSC-BAPs.This novel culture system provides an unlimited source of human brown adipocytes and a unique means for studying events regulating the generation and recruitment of human BAPs.

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Keywords:  Adipocyte; Adipocyte progenitors; Brown adipocytes; Differentiation; Human induced pluripotent stem cells

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Year:  2018        PMID: 29687379     DOI: 10.1007/978-1-4939-7799-4_4

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  1 in total

Review 1.  Human Pluripotent Stem Cells: A Relevant Model to Identify Pathways Governing Thermogenic Adipocyte Generation.

Authors:  Xi Yao; Vincent Dani; Christian Dani
Journal:  Front Endocrinol (Lausanne)       Date:  2020-01-21       Impact factor: 5.555

  1 in total

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