Literature DB >> 29686569

Pedunculated focal nodular hyperplasia in a healthy toddler.

Juhi Koolwal1, Krista L Birkemeier2, Riyam T Zreik3, Kelly D Mattix4.   

Abstract

Focal nodular hyperplasia (FNH) is a benign hepatic tumor rarely seen in pediatric patients, with most cases reported in school-aged children with a history of malignancy, liver disease, chemotherapy, or hematopoietic stem cell therapy. Despite having advanced radiographic imaging, diagnosing FNH before surgical resection can be difficult. We report a rare case of pedunculated FNH presenting as a large abdominal mass palpated on physical exam in a healthy 3-year-old girl with no history of malignancy or underlying liver disease. Ultrasound, computed tomography, and magnetic resonance imaging (MRI) did not demonstrate the typical imaging characteristics of FNH, because the mass was pedunculated with a poorly visualized central scar. Because approximately 75% of all primary hepatic tumors in this age group are malignant, this report also discusses the importance of adding hepatobiliary phase imaging with MRI to avoid, if possible, the need for biopsy or surgical resection of a benign hepatic tumor.

Entities:  

Keywords:  Focal nodular hyperplasia; hepatic tumor; hepatobiliary phase imaging

Year:  2018        PMID: 29686569      PMCID: PMC5903535          DOI: 10.1080/08998280.2017.1401845

Source DB:  PubMed          Journal:  Proc (Bayl Univ Med Cent)        ISSN: 0899-8280


  8 in total

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Authors:  S Sawhney; R Jain; R Safaya; M Berry
Journal:  Pediatr Radiol       Date:  1992

Review 2.  Focal nodular hyperplasia in children: an institutional experience with review of the literature.

Authors:  Irene T Ma; Yesenia Rojas; Prakash M Masand; Eumenia C Castro; Ryan W Himes; Eugene S Kim; John A Goss; Jed G Nuchtern; Milton J Finegold; Patrick A Thompson; Sanjeev A Vasudevan
Journal:  J Pediatr Surg       Date:  2014-08-27       Impact factor: 2.545

3.  Characterization of pediatric liver lesions with gadoxetate disodium.

Authors:  Arthur B Meyers; Alexander J Towbin; Suraj Serai; James I Geller; Daniel J Podberesky
Journal:  Pediatr Radiol       Date:  2011-06-24

4.  From the archives of the AFIP: Pediatric liver masses: radiologic-pathologic correlation part 1. Benign tumors.

Authors:  Ellen M Chung; Regino Cube; Rachel B Lewis; Richard M Conran
Journal:  Radiographics       Date:  2010-05       Impact factor: 5.333

Review 5.  Hepatoblastoma imaging with gadoxetate disodium-enhanced MRI--typical, atypical, pre- and post-treatment evaluation.

Authors:  Arthur B Meyers; Alexander J Towbin; James I Geller; Daniel J Podberesky
Journal:  Pediatr Radiol       Date:  2012-03-15

6.  Gadobenate-dimeglumine-enhanced magnetic resonance imaging for hepatic lesions in children.

Authors:  Govind B Chavhan; Erika Mann; Binita M Kamath; Paul S Babyn
Journal:  Pediatr Radiol       Date:  2014-04-27

7.  Focal nodular hyperplasia of the liver: a study of 21 pediatric cases.

Authors:  J T Stocker; K G Ishak
Journal:  Cancer       Date:  1981-07-15       Impact factor: 6.860

Review 8.  MRI of paediatric liver tumours: How we review and report.

Authors:  Susan C Shelmerdine; Derek J Roebuck; Alexander J Towbin; Kieran McHugh
Journal:  Cancer Imaging       Date:  2016-08-15       Impact factor: 3.909

  8 in total

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