Literature DB >> 29686552

Myocardial ischemia in an adolescent secondary to nutritional thiamine deficiency.

Cassandra Lefevre1, Lea H Mallett1, Lori Wick1.   

Abstract

Thiamine (vitamin B1) is an essential vitamin found in most food products in developed nations. Deficiencies in this crucial vitamin lead to diseases related to nutritional needs, metabolic demands, enzymatic function, and neurological inflammation. We present an 18-year-old patient with a history of nasopharyngeal carcinoma and total parenteral nutrition (TPN) dependence who experienced neurological manifestations and heart failure, likely due to underlying thiamine deficiency, dehydration, and vasodilation. The patient exhibited heart failure due to thiamine deficiency that was overlooked by her care team secondary to a reaction to preservatives associated with vitamins in TPN, lapse in communication, and decreased compliance.

Entities:  

Keywords:  Myocardial ischemia; thiamine deficiency; total parenteral nutrition; vitamin B1

Year:  2018        PMID: 29686552      PMCID: PMC5903537          DOI: 10.1080/08998280.2017.1401343

Source DB:  PubMed          Journal:  Proc (Bayl Univ Med Cent)        ISSN: 0899-8280


  6 in total

Review 1.  Thiamine deficiency: an update of pathophysiologic mechanisms and future therapeutic considerations.

Authors:  Eman Abdou; Alan S Hazell
Journal:  Neurochem Res       Date:  2014-10-09       Impact factor: 3.996

2.  Severe lactic acidosis and multiorgan failure due to thiamine deficiency during total parenteral nutrition.

Authors:  Musaab Ramsi; Claire Mowbray; Gary Hartman; Natalie Pageler
Journal:  BMJ Case Rep       Date:  2014-06-03

3.  Lactic acidosis traced to thiamine deficiency related to nationwide shortage of multivitamins for total parenteral nutrition -- United States, 1997.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  1997-06-13       Impact factor: 17.586

4.  Thiamine-responsive myelodysplasia.

Authors:  A Bazarbachi; S Muakkit; M Ayas; A Taher; Z Salem; H Solh; J H Haidar
Journal:  Br J Haematol       Date:  1998-09       Impact factor: 6.998

5.  Thiamine deficiency secondary to anorexia nervosa: an uncommon cause of peripheral neuropathy and Wernicke encephalopathy in adolescence.

Authors:  William Renthal; Isaac Marin-Valencia; Patricia A Evans
Journal:  Pediatr Neurol       Date:  2014-03-30       Impact factor: 3.372

6.  Severe acute metabolic acidosis (acute beriberi): an avoidable complication of total parenteral nutrition.

Authors:  R J Velez; B Myers; M S Guber
Journal:  JPEN J Parenter Enteral Nutr       Date:  1985 Mar-Apr       Impact factor: 4.016

  6 in total
  1 in total

Review 1.  Pediatric thiamine deficiency disorders in high-income countries between 2000 and 2020: a clinical reappraisal.

Authors:  Benjamin Rakotoambinina; Laurent Hiffler; Filomena Gomes
Journal:  Ann N Y Acad Sci       Date:  2021-07-26       Impact factor: 6.499

  1 in total

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