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Literature DB >> 29685971

Epigenetics: the first 25 centuries.

Abstract

Epigenetics is a natural progression of genetics as it aims to understand how genes and other heritable elements are regulated in eukaryotic organisms. The history of epigenetics is briefly reviewed, together with the key issues in the field today. This themed issue brings together a diverse collection of interdisciplinary reviews and research articles that showcase the tremendous recent advances in epigenetic chemical biology and translational research into epigenetic drug discovery.This article is part of a discussion meeting issue 'Frontiers in epigenetic chemical biology'.

Keywords: epigenetics; genetics

Mesh：

Year: 2018 PMID： 29685971 PMCID： PMC5915711 DOI： 10.1098/rstb.2017.0067

Source DB: PubMed Journal: Philos Trans R Soc Lond B Biol Sci ISSN： 0962-8436 Impact factor: 6.237

18 in total

1. Celebrating the genetic jubilee: a conversation with James D. Watson. Interviewed by John Rennie.

Authors: James D Watson
Journal: Sci Am Date: 2003-04 Impact factor: 2.142

Review 2. Epigenetic drug discovery: a success story for cofactor interference.

Authors: A Ganesan
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2018-06-05 Impact factor: 6.237

3. In silico epigenetics of metal exposure and subclinical atherosclerosis in middle aged men: pilot results from the Aragon Workers Health Study.

Authors: Angela L Riffo-Campos; Azahara Fuentes-Trillo; Wan Y Tang; Zoraida Soriano; Griselda De Marco; Pilar Rentero-Garrido; Victoria Adam-Felici; Veronica Lendinez-Tortajada; Kevin Francesconi; Walter Goessler; Christine Ladd-Acosta; Montse Leon-Latre; Jose A Casasnovas; F Javier Chaves; Ana Navas-Acien; Eliseo Guallar; Maria Tellez-Plaza
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2018-06-05 Impact factor: 6.237

4. Germ cell tumour subtypes display differential expression of microRNA371a-3p.

Authors: Bárbara Vilela-Salgueiro; Daniela Barros-Silva; João Lobo; Ana Laura Costa; Rita Guimarães; Mariana Cantante; Paula Lopes; Isaac Braga; Jorge Oliveira; Rui Henrique; Carmen Jerónimo
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2018-06-05 Impact factor: 6.237

5. Desferrioxamine biosynthesis: diverse hydroxamate assembly by substrate-tolerant acyl transferase DesC.

Authors: Jade L Ronan; Nadia Kadi; Stephen A McMahon; James H Naismith; Lona M Alkhalaf; Gregory L Challis
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2018-06-05 Impact factor: 6.237

6. Isoform-selective HDAC1/6/8 inhibitors with an imidazo-ketopiperazine cap containing stereochemical diversity.

Authors: Bertrand Lecointre; Remy Narozny; Maria Teresa Borrello; Johanna Senger; Alokta Chakrabarti; Manfred Jung; Martin Marek; Christophe Romier; Jelena Melesina; Wolfgang Sippl; Laurent Bischoff; A Ganesan
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2018-06-05 Impact factor: 6.237

7. Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells.

Authors: Paolo Mellini; Biagina Marrocco; Diana Borovika; Lucia Polletta; Ilaria Carnevale; Serena Saladini; Giulia Stazi; Clemens Zwergel; Peteris Trapencieris; Elisabetta Ferretti; Marco Tafani; Sergio Valente; Antonello Mai
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2018-06-05 Impact factor: 6.237

8. New chemical tools for probing activity and inhibition of the NAD⁺-dependent lysine deacylase sirtuin 2.

Authors: Sören Swyter; Matthias Schiedel; Daria Monaldi; Sándor Szunyogh; Attila Lehotzky; Tobias Rumpf; Judit Ovádi; Wolfgang Sippl; Manfred Jung
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2018-06-05 Impact factor: 6.237

9. Inhibitors of both the N-methyl lysyl- and arginyl-demethylase activities of the JmjC oxygenases.

Authors: Joanna Bonnici; Anthony Tumber; Akane Kawamura; Christopher J Schofield
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2018-06-05 Impact factor: 6.237

Review 10. Protein methyltransferase inhibitors as precision cancer therapeutics: a decade of discovery.

Authors: Robert A Copeland
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2018-06-05 Impact factor: 6.237

5 in total

Review 1. Back to the Colorectal Cancer Consensus Molecular Subtype Future.

Authors: David G Menter; Jennifer S Davis; Bradley M Broom; Michael J Overman; Jeffrey Morris; Scott Kopetz
Journal: Curr Gastroenterol Rep Date: 2019-01-30

Review 2. Epigenetic Regulation Associated With Sirtuin 1 in Complications of Diabetes Mellitus.

Authors: Jie Wang A; Shudong Wang; Jie Wang B; Mengjie Xiao; Yuanfang Guo; Yufeng Tang; Jingjing Zhang; Junlian Gu
Journal: Front Endocrinol (Lausanne) Date: 2021-01-18 Impact factor: 5.555

3. Epigenetic differences of chronic hepatitis B in different TCM syndromes: Protocol for a case-control, non-interventional, observational clinical study.

Authors: Li Ma; Xiuli Zheng; Yu Yang; Jian Wang; Youli Xu; Baojia Wang
Journal: Medicine (Baltimore) Date: 2018-09 Impact factor: 1.889

Review 4. From Single Level Analysis to Multi-Omics Integrative Approaches: A Powerful Strategy towards the Precision Oncology.

Authors: Maria Eugenia Gallo Cantafio; Katia Grillone; Daniele Caracciolo; Francesca Scionti; Mariamena Arbitrio; Vito Barbieri; Licia Pensabene; Pietro Hiram Guzzi; Maria Teresa Di Martino
Journal: High Throughput Date: 2018-10-26

Review 5. Ten Years of EWAS.

Authors: Siyu Wei; Junxian Tao; Jing Xu; Xingyu Chen; Zhaoyang Wang; Nan Zhang; Lijiao Zuo; Zhe Jia; Haiyan Chen; Hongmei Sun; Yubo Yan; Mingming Zhang; Hongchao Lv; Fanwu Kong; Lian Duan; Ye Ma; Mingzhi Liao; Liangde Xu; Rennan Feng; Guiyou Liu; The Ewas Project; Yongshuai Jiang
Journal: Adv Sci (Weinh) Date: 2021-08-11 Impact factor: 16.806

5 in total