Literature DB >> 29685853

A successful antimicrobial therapeutic strategy for the discitis caused by Aggregatibacter actinomycetemcomitans under unknown drug susceptibility: A case report.

Shunsuke Uno1, Yosuke Horiuchi2, Takae Uchida3, Akiko Yonaha4, Takanori Miyata5, Eiko Nagano6, Takao Kodama2, Naoki Hasegawa7.   

Abstract

Aggregatibacter actinomycetemcomitans is well-known as the pathogen of gingivitis or periodontitis, and discitis or vertebral osteomyelitis cases caused by this organism have rarely been reported. Ampicillin or amoxicillin has been used in the previously reported discitis cases; however, no cases have been reported that is treated with levofloxacin. We report the first published case we chose levofloxacin to treat. We failed to perform the susceptibility testing because of the poor growth and fastidious nature of the organism, and the result of susceptibility of amoxicillin was unclear. Levofloxacin, which A. actinomycetemcomitans is usually susceptible to, can be an effective alternative oral antimicrobial agent in such cases.
Copyright © 2018 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Aggregatibacter actinomycetemcomitans; Discitis; Levofloxacin; Quinolone

Mesh:

Substances:

Year:  2018        PMID: 29685853     DOI: 10.1016/j.jiac.2018.03.013

Source DB:  PubMed          Journal:  J Infect Chemother        ISSN: 1341-321X            Impact factor:   2.211


  1 in total

1.  Spontaneous Pyogenic Spondylitis and Possible Infective Endocarditis Caused by Aggregatibacter actinomycetemcomitans.

Authors:  Naoko Yukihira; Hiroshi Hori; Takeshi Yamashita; Ai Kawamura; Takahiko Fukuchi; Hitoshi Sugawara
Journal:  Intern Med       Date:  2020-12-15       Impact factor: 1.271

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.