Literature DB >> 2968280

Shift in rat liver glycolysis control from fed to starved conditions. Flux control coefficients of glucokinase and phosphofructokinase.

N V Torres1, F Mateo, E Meléndez-Hevia.   

Abstract

The distribution of flux control coefficients of a glycolytic system in starved rat liver has been determined. The flux control coefficient profile in starved conditions is compared with normal fed conditions showing that in the former phosphofructokinase enhances more than 2-fold its flux control coefficient while glucokinase decreases slightly. The results also show that the starved system has a more complex structure probably because of the greater influence on the flux of the reverse substrate cycles and the synthesis and degradation fructose 2,6-bisphosphate reactions.

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Year:  1988        PMID： 2968280     DOI： 10.1016/0014-5793(88)81360-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  7 in total

1.  Control analysis of rat liver glycolysis under different glucose concentrations. The substrate approach and the role of glucokinase.

Authors:  E Meléndez-Hevia; F Mateo; N V Torres
Journal:  Mol Cell Biochem       Date:  1992-09-22       Impact factor: 3.396

2.  Detailed protocol and critical view for the analysis of control in metabolic systems by shortening and enzyme titration.

Authors:  N V Torres; E Meléndez-Hevia
Journal:  Mol Cell Biochem       Date:  1991-02-27       Impact factor: 3.396

3.  Glycolysis activity in flight muscles of birds according to their physiological function. An experimental model in vitro to study aerobic and anaerobic glycolysis activity separately.

Authors:  David Meléndez-Morales; Patricia de Paz-Lugo; Enrique Meléndez-Hevia
Journal:  Mol Cell Biochem       Date:  2009-03-26       Impact factor: 3.396

4.  Control of glycolysis in rat liver by glucokinase and phosphofructokinase: influence of glucose concentration.

Authors:  N V Torres; F Mateo; J M Riol-Cimas; E Meléndez-Hevia
Journal:  Mol Cell Biochem       Date:  1990-03-05       Impact factor: 3.396

5.  Study of the flux and transition time control coefficient profiles in a metabolic system in vitro and the effect of an external stimulator.

Authors:  N V Torres; R Souto; E Meléndez-Hevia
Journal:  Biochem J       Date:  1989-06-15       Impact factor: 3.857

6.  Optimization of molecular design in the evolution of metabolism: the glycogen molecule.

Authors:  E Meléndez-Hevia; T G Waddell; E D Shelton
Journal:  Biochem J       Date:  1993-10-15       Impact factor: 3.857

7.  The futile cycling of hexose phosphates could account for the fact that hexokinase exerts a high control on glucose phosphorylation but not on glycolytic rate in transgenic potato (Solanum tuberosum) roots.

Authors:  Eric Claeyssen; Sonia Dorion; Audrey Clendenning; Jiang Zhou He; Owen Wally; Jingkui Chen; Evgenia L Auslender; Marie-Claude Moisan; Mario Jolicoeur; Jean Rivoal
Journal:  PLoS One       Date:  2013-01-28       Impact factor: 3.240
  7 in total

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