| Literature DB >> 2968279 |
O Vuolteenaho1, O Arjamaa, O Vakkuri, T Maksniemi, L Nikkilä, J Kangas, J Puurunen, H Ruskoaho, J Leppäluoto.
Abstract
Acid extracts of rat stomach and small intestine contained 8.6 +/- 3.7 and 39 +/- 15 ng/g of immunoreactive atrial natriuretic peptide (ANP). When studied by gel filtration and reverse-phase high-performance liquid chromatography, the stomach immunoreactivity consisted of multiple components, whereas the small intestine contained mostly proANP and ANP 1-28-like material. These findings indicate that ANP may have a role in the physiology of the gastrointestinal tract, e.g. in the regulation of water and electrolyte absorption.Entities:
Mesh:
Substances:
Year: 1988 PMID: 2968279 DOI: 10.1016/0014-5793(88)81359-0
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124