Physicochemical methods for detection of contact allergens.

In the same way that it often is necessary to perform chemical and biological analysis of skin and body fluids in the management of skin disease, it may be necessary to analyze the chemical environment. Some analyses, such as those for nickel, chromate, and formaldehyde, require only simple tests. Others require complex and expensive equipment and specialized skills. In the future, it may become necessary to install some of this equipment for routine use in dermatology clinics. In the meantime, the dermatologist needs to be aware of the possibilities.