Literature DB >> 29680634

The Dual Face of Cyclin B1.

Arp Schnittger1, Lieven De Veylder2.   

Abstract

Although widely used as a marker for cell proliferation, CYCB1;1 expression is also strongly induced in cells that suffer from DNA damage. Recently, this enigmatic dual expression pattern has been resolved by proving that CYCB1;1 promotes DNA repair. This has consequences for using CYCB1;1 as a cell cycle reporter.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  CYCB1;1; cell proliferation; homologous recombination

Mesh:

Substances:

Year:  2018        PMID: 29680634     DOI: 10.1016/j.tplants.2018.03.015

Source DB:  PubMed          Journal:  Trends Plant Sci        ISSN: 1360-1385            Impact factor:   18.313


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