Ruihua Liu1, Yuqian Li2, Zhenxing Mao1, Xiaotian Liu1, Haiqing Zhang1, Kaili Yang1, Honglei Zhang1, Runqi Tu1, Xinling Qian1, Jingjing Jiang1, Ronghai Bie3, Chongjian Wang4. 1. Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Henan, PR China. 2. Department of Clinical Pharmacology, School of Pharmaceutical Science, Zhengzhou University, Henan, PR China. 3. Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Henan, PR China. Electronic address: bierh2012@126.com. 4. Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Henan, PR China. Electronic address: tjwcj2005@126.com.
Abstract
OBJECTIVE: The aim of this study was to explore the independent and combined dose-response association of napping and night sleep duration with type 2 diabetes mellitus (T2DM) among different genders in the rural Chinese population. METHODS: For this research, a total of 19,257 participants were enrolled in the Rural Diabetes, Obesity and Lifestyle (RuralDiab) study. Napping and night sleep duration were assessed using the Pittsburgh Sleep Quality Index (PSQI). Restricted cubic splines and logistic regression were used to estimate the relationship between napping and night sleep duration with T2DM. RESULTS: A linear dose-response relationship between napping duration and T2DM as well as a U-shaped relationship between night sleep duration and T2DM were found. Compared with those who reported no napping, participants who had a napping duration of ≥91 min were associated with a 19% increase in prevalence of T2DM. Adjusted odds ratios (ORs) (95% confidence intervals (CIs)) for T2DM were 1.48 (1.03, 2.14) and 1.50 (1.22, 1.85) for shorter (≤5 h) and longer (>9 h) night sleep duration compared with the referential group. Additionally, the combination of longer napping duration (≥91 min) and night sleep duration (>9 h) increased 104% (95% CI: 45%, 128%) prevalence for T2DM. These associations were not found in males but were evident in females. CONCLUSIONS: Longer napping duration and extreme night sleep duration increased the prevalence of T2DM. Meanwhile, longer napping and night sleep duration might be jointly associated with a higher prevalence of T2DM.
OBJECTIVE: The aim of this study was to explore the independent and combined dose-response association of napping and night sleep duration with type 2 diabetes mellitus (T2DM) among different genders in the rural Chinese population. METHODS: For this research, a total of 19,257 participants were enrolled in the Rural Diabetes, Obesity and Lifestyle (RuralDiab) study. Napping and night sleep duration were assessed using the Pittsburgh Sleep Quality Index (PSQI). Restricted cubic splines and logistic regression were used to estimate the relationship between napping and night sleep duration with T2DM. RESULTS: A linear dose-response relationship between napping duration and T2DM as well as a U-shaped relationship between night sleep duration and T2DM were found. Compared with those who reported no napping, participants who had a napping duration of ≥91 min were associated with a 19% increase in prevalence of T2DM. Adjusted odds ratios (ORs) (95% confidence intervals (CIs)) for T2DM were 1.48 (1.03, 2.14) and 1.50 (1.22, 1.85) for shorter (≤5 h) and longer (>9 h) night sleep duration compared with the referential group. Additionally, the combination of longer napping duration (≥91 min) and night sleep duration (>9 h) increased 104% (95% CI: 45%, 128%) prevalence for T2DM. These associations were not found in males but were evident in females. CONCLUSIONS: Longer napping duration and extreme night sleep duration increased the prevalence of T2DM. Meanwhile, longer napping and night sleep duration might be jointly associated with a higher prevalence of T2DM.
Authors: Anna Brzecka; Natalia Madetko; Vladimir N Nikolenko; Ghulam M Ashraf; Maria Ejma; Jerzy Leszek; Cyryl Daroszewski; Karolina Sarul; Liudmila M Mikhaleva; Siva G Somasundaram; Cecil E Kirkland; Sergey O Bachurin; Gjumrakch Aliev Journal: Curr Neuropharmacol Date: 2021 Impact factor: 7.363