Literature DB >> 29676909

18F-Positron Emitting/Trimethine Cyanine-Fluorescent Contrast for Image-Guided Prostate Cancer Management.

Harikrishna Kommidi1, Hua Guo1, Fuad Nurili2, Yogindra Vedvyas1, Moonsoo M Jin1, Timothy D McClure3, Behfar Ehdaie4, Haluk B Sayman5, Oguz Akin2, Omer Aras2, Richard Ting1.   

Abstract

[18/19F]-4, an anionic GCPII/PSMA inhibitor for image-guided intervention in prostate cancer, is described. [19F]-4 is radiolabeled with a radiochemical yield that is ≥27% and a molar activity of 190 ± 50 mCi/μmol in a <1 h, one-step, aqueous isotopic exchange reaction. [19F]-4 allows PSMA expression to be imaged by fluorescence (FL) and [18F]-PET. PC3-PIP (PSMA-positive, EC50 = 6.74 ± 1.33 nM) cancers are specifically delineated in mice that bear 3 million (18 mg) PC3-PIP and PC3 (control, PSMA-negative) cells. Colocalization of [18/19F]-4 PET, fluorescence, scintillated biodistribution, and PSMA expression are observed.

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Year:  2018        PMID： 29676909      PMCID： PMC6263152          DOI： 10.1021/acs.jmedchem.8b00240

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


  33 in total

1.  18F-labeling of peptides by means of an organosilicon-based fluoride acceptor.

Authors:  Ralf Schirrmacher; Gerrit Bradtmöller; Esther Schirrmacher; Oliver Thews; Julia Tillmanns; Thomas Siessmeier; Hans G Buchholz; Peter Bartenstein; Björn Wängler; Christof M Niemeyer; Klaus Jurkschat
Journal:  Angew Chem Int Ed Engl       Date:  2006-09-11       Impact factor: 15.336

2.  From minutes to years: predicting organotrifluoroborate solvolysis rates.

Authors:  Zhibo Liu; Daniel Chao; Ying Li; Richard Ting; Jihyoon Oh; David M Perrin
Journal:  Chemistry       Date:  2015-01-30       Impact factor: 5.236

3.  68Ga-complex lipophilicity and the targeting property of a urea-based PSMA inhibitor for PET imaging.

Authors:  Matthias Eder; Martin Schäfer; Ulrike Bauder-Wüst; William-Edmund Hull; Carmen Wängler; Walter Mier; Uwe Haberkorn; Michael Eisenhut
Journal:  Bioconjug Chem       Date:  2012-03-13       Impact factor: 4.774

4.  Targeted, activatable, in vivo fluorescence imaging of prostate-specific membrane antigen (PSMA) positive tumors using the quenched humanized J591 antibody-indocyanine green (ICG) conjugate.

Authors:  Takahito Nakajima; Makoto Mitsunaga; Neil H Bander; Warren D Heston; Peter L Choyke; Hisataka Kobayashi
Journal:  Bioconjug Chem       Date:  2011-07-27       Impact factor: 4.774

5.  High-affinity near-infrared fluorescent small-molecule contrast agents for in vivo imaging of prostate-specific membrane antigen.

Authors:  Valerie Humblet; Rena Lapidus; Larry R Williams; Takashi Tsukamoto; Camilo Rojas; Pavel Majer; Bunda Hin; Shunsuke Ohnishi; Alec M De Grand; Atif Zaheer; Jürgen T Renze; Akira Nakayama; Barbara S Slusher; John V Frangioni
Journal:  Mol Imaging       Date:  2005 Oct-Dec       Impact factor: 4.488

6.  Preclinical Evaluation of a Tailor-Made DOTA-Conjugated PSMA Inhibitor with Optimized Linker Moiety for Imaging and Endoradiotherapy of Prostate Cancer.

Authors:  Martina Benešová; Martin Schäfer; Ulrike Bauder-Wüst; Ali Afshar-Oromieh; Clemens Kratochwil; Walter Mier; Uwe Haberkorn; Klaus Kopka; Matthias Eder
Journal:  J Nucl Med       Date:  2015-04-16       Impact factor: 10.057

7.  Prostate cancer in elderly men.

Authors:  Anton Stangelberger; Matthias Waldert; Bob Djavan
Journal:  Rev Urol       Date:  2008

8.  Cancer statistics, 2009.

Authors:  Ahmedin Jemal; Rebecca Siegel; Elizabeth Ward; Yongping Hao; Jiaquan Xu; Michael J Thun
Journal:  CA Cancer J Clin       Date:  2009-05-27       Impact factor: 508.702

Review 9.  From Unorthodox to Established: The Current Status of (18)F-Trifluoroborate- and (18)F-SiFA-Based Radiopharmaceuticals in PET Nuclear Imaging.

Authors:  Vadim Bernard-Gauthier; Justin J Bailey; Zhibo Liu; Björn Wängler; Carmen Wängler; Klaus Jurkschat; David M Perrin; Ralf Schirrmacher
Journal:  Bioconjug Chem       Date:  2015-11-25       Impact factor: 4.774

10.  Synthesis and preclinical evaluation of DOTAGA-conjugated PSMA ligands for functional imaging and endoradiotherapy of prostate cancer.

Authors:  Martina Weineisen; Jakub Simecek; Margret Schottelius; Markus Schwaiger; Hans-Jürgen Wester
Journal:  EJNMMI Res       Date:  2014-11-25       Impact factor: 3.138
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  14 in total

Review 1.  Fluorescence Guidance in Surgical Oncology: Challenges, Opportunities, and Translation.

Authors:  Madeline T Olson; Quan P Ly; Aaron M Mohs
Journal:  Mol Imaging Biol       Date:  2019-04       Impact factor: 3.488

2.  A Fluorescent, [18F]-Positron-Emitting Agent for Imaging Prostate-Specific Membrane Antigen Allows Genetic Reporting in Adoptively Transferred, Genetically Modified Cells.

Authors:  Hua Guo; Harikrishna Kommidi; Yogindra Vedvyas; Jaclyn E McCloskey; Weiqi Zhang; Nandi Chen; Fuad Nurili; Amy P Wu; Haluk B Sayman; Oguz Akin; Erik A Rodriguez; Omer Aras; Moonsoo M Jin; Richard Ting
Journal:  ACS Chem Biol       Date:  2019-06-17       Impact factor: 5.100

Review 3.  Comparison of prostate-specific membrane antigen ligands in clinical translation research for diagnosis of prostate cancer.

Authors:  Sagnik Sengupta; Mena Asha Krishnan; Sudeshna Chattopadhyay; Venkatesh Chelvam
Journal:  Cancer Rep (Hoboken)       Date:  2019-04-02

4.  Hybrid Tracers Based on Cyanine Backbones Targeting Prostate-Specific Membrane Antigen: Tuning Pharmacokinetic Properties and Exploring Dye-Protein Interaction.

Authors:  Albertus W Hensbergen; Tessa Buckle; Danny M van Willigen; Margret Schottelius; Mick M Welling; Felicia A van der Wijk; Tobias Maurer; Henk G van der Poel; Gabri van der Pluijm; Wytske M van Weerden; Hans-Jürgen Wester; Fijs W B van Leeuwen
Journal:  J Nucl Med       Date:  2019-09-03       Impact factor: 10.057

5.  Simultaneous injection of 18F-BF3- Cy3-ACUPA and non-radioactive Cy7-ACUPA probes: a promising pre-biopsy PET and ex vivo fluorescence imaging approach to evaluate prostate cancer.

Authors:  Omer Aras; Cetin Demirdag; Harikrishna Kommidi; Ina Pavlova; Vitaly Boyko; Dara J Lundon; Richard Ting; Ashutosh Tewari; Oguz Akin; Haluk B Sayman
Journal:  Eur J Nucl Med Mol Imaging       Date:  2021-04-16       Impact factor: 10.057

Review 6.  1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview.

Authors:  Khurshed Bozorov; Jiangyu Zhao; Haji A Aisa
Journal:  Bioorg Med Chem       Date:  2019-07-04       Impact factor: 3.641

7.  Image-Guided Surgery: Are We Getting the Most Out of Small-Molecule Prostate-Specific-Membrane-Antigen-Targeted Tracers?

Authors:  Albertus Wijnand Hensbergen; Danny M van Willigen; Florian van Beurden; Pim J van Leeuwen; Tessa Buckle; Margret Schottelius; Tobias Maurer; Hans-Jürgen Wester; Fijs W B van Leeuwen
Journal:  Bioconjug Chem       Date:  2020-01-06       Impact factor: 4.774

8.  New potent steroid sulphatase inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives.

Authors:  Olga Ciupak; Mateusz Daśko; Karol Biernacki; Janusz Rachon; Maciej Masłyk; Konrad Kubiński; Aleksandra Martyna; Sebastian Demkowicz
Journal:  J Enzyme Inhib Med Chem       Date:  2021-12       Impact factor: 5.051

Review 9.  PSMA-targeting agents for radio- and fluorescence-guided prostate cancer surgery.

Authors:  Yvonne H W Derks; Dennis W P M Löwik; J P Michiel Sedelaar; Martin Gotthardt; Otto C Boerman; Mark Rijpkema; Susanne Lütje; Sandra Heskamp
Journal:  Theranostics       Date:  2019-09-20       Impact factor: 11.556

Review 10.  Convection Enhanced Delivery for Diffuse Intrinsic Pontine Glioma: Review of a Single Institution Experience.

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Journal:  Pharmaceutics       Date:  2020-07-14       Impact factor: 6.321
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