| Literature DB >> 29676594 |
Zhi-Wei Wang1, Yun Li1,2, Da-Hui Liu3, Yan Mu1, Hong-Jing Dong1, Hong-Lei Zhou2, Lan-Ping Guo1, Xiao Wang1.
Abstract
Four new gastrodin derivatives containing a trans-cinnamoyl unit (1-4) and nine known compounds (5-13) were isolated from the rhizomes of Gastrodia elata Blume. All these compounds were evaluated for their neuroprotective effects against 6-hydroxydopamine-induced cell death, and compounds 7 and 12 showed potent activities with EC50 values of 10.5 and 10.2 μM, respectively.Entities:
Keywords: -(4-hydroxybenzyl) adenosine; Blume; Phenolics; grossamide; neuroprotective effects
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Year: 2018 PMID： 29676594 DOI： 10.1080/14786419.2018.1460836
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861