Literature DB >> 29675091

Cranial Nerve Involvement in Guillain-Barre Syndrome: Revisited.

Khichar Purnaram Shubhakaran1.   

Abstract

Entities:  

Year:  2017        PMID: 29675091      PMCID: PMC5890572          DOI: 10.4103/jpn.JPN_18_17

Source DB:  PubMed          Journal:  J Pediatr Neurosci        ISSN: 1817-1745


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Dear Sir, We read an interesting case report by Ray and Jain.[1] The eminent authors have reported a case of Guillain–Barre Syndrome (GBS) presenting as bulbar palsy plus syndrome. Here, we would like to share our experience and views: Cranial nerve involvement is said to be rare (5%), especially in children by the authors[1] and supported by another reference.[2] We in a prospective study of 61 patients in the age range of 8–78 years, found bulbar palsy in 46.2%, facial palsy in 46%, tongue weakness in 10%, unilateral facial palsy in (3 patients) 5%, ophthalmoplegia in 6.4%, and sensorineural deafness (eighth cranial nerve involvement) in 1 patient.[3] Our observations are almost similar to the earlier text references[4] The authors have said that unilateral facial palsy in GBS is extremely rare, especially in children. We in our study which also included pediatric population found unilateral facial palsy in (three patients) 5% of the patients[3] The present study also concluded that there is a correlation between cranial nerve palsy and severity of GBS, and bulbar palsy is an indicator of respiratory involvement. Careful search of the cranial nerve involvement may yield more and more cranial neuropathies[3] As bulbar involvement is an indicator of impending respiratory involvement, the index case of the eminent authors was lucky enough not have such complication. One reason may be that the patient’s illness stabilized after initial progression for 4 days.

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  4 in total

1.  Clinical variants of Guillain-Barré syndrome in children.

Authors:  Jainn-Jim Lin; Shao-Hsuan Hsia; Huei-Shyong Wang; Rong-Kuo Lyu; Min-Liang Chou; Po-Cheng Hung; Meng-Ying Hsieh; Kuang-Lin Lin
Journal:  Pediatr Neurol       Date:  2012-08       Impact factor: 3.372

Review 2.  Guillain-Barré syndrome and variants.

Authors:  Mazen M Dimachkie; Richard J Barohn
Journal:  Neurol Clin       Date:  2013-02-19       Impact factor: 3.806

3.  A study of Guillain-Barré syndrome with reference to cranial neuropathy and its prognostic implication.

Authors:  Amita Bhargava; Basavaraj F Banakar; Guruprasad S Pujar; Shubhakaran Khichar
Journal:  J Neurosci Rural Pract       Date:  2014-11

4.  Acute bulbar palsy plus syndrome: A rare variant of Guillain-Barre syndrome.

Authors:  Sanghamitra Ray; Prakash Chand Jain
Journal:  J Pediatr Neurosci       Date:  2016 Oct-Dec
  4 in total

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