Literature DB >> 29671279

Brief Report: Lupus-An Unrecognized Leading Cause of Death in Young Females: A Population-Based Study Using Nationwide Death Certificates, 2000-2015.

Eric Y Yen1, Ram R Singh1.   

Abstract

OBJECTIVE: Mortality statistics from the Centers for Disease Control and Prevention (CDC) are used for planning health care policy and allocating resources. The CDC uses these data to compile its annual ranking of leading causes of death based on a selected list of 113 causes. Systemic lupus erythematosus (SLE) is not included on this list. Since the ranking is a useful tool for assessing the relative burden of cause-specific mortality, this study was undertaken to rank SLE deaths among the CDC's leading causes of death to see whether SLE is a significant cause of death among females.
METHODS: Death counts for the female population of the US were obtained from the CDC's Wide-ranging Online Data for Epidemiologic Research database and then grouped by age and race/ethnicity. Data on the leading causes of death were obtained from the Web-based Injury Statistics Query and Reporting System database.
RESULTS: During 2000-2015, there were 28,411 deaths of females with SLE recorded as an underlying or contributing cause of death. SLE ranked among the top 20 leading causes of death in females between 5 and 64 years of age. SLE ranked tenth among those ages 15-24 years, fourteenth among those ages 25-34 years and 35-44 years, and fifteenth among those ages 10-14 years. For African American and Hispanic females, SLE ranked fifth among those ages 15-24 years, sixth among those ages 25-34 years, and eighth or ninth among those ages 35-44 years, after the 3 common external injury causes of death were excluded from the analysis.
CONCLUSION: SLE is among the leading causes of death in young females, underscoring its impact as an important public health issue.
© 2018, American College of Rheumatology.

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Year:  2018        PMID: 29671279      PMCID: PMC6105528          DOI: 10.1002/art.40512

Source DB:  PubMed          Journal:  Arthritis Rheumatol        ISSN: 2326-5191            Impact factor:   10.995


  6 in total

1.  Lack of recording of systemic lupus erythematosus in the death certificates of lupus patients.

Authors:  J Calvo-Alén; G S Alarcón; R Campbell; M Fernández; J D Reveille; G S Cooper
Journal:  Rheumatology (Oxford)       Date:  2005-06-14       Impact factor: 7.580

2.  Cardiovascular disease a hazard despite improved prognosis in patients with systemic lupus erythematosus: results from a Swedish population based study 1964-95.

Authors:  Lena Björnådal; Li Yin; Fredrik Granath; Lars Klareskog; Anders Ekbom
Journal:  J Rheumatol       Date:  2004-04       Impact factor: 4.666

3.  Education level and mortality in systemic lupus erythematosus (SLE): evidence of underascertainment of deaths due to SLE in ethnic minorities with low education levels.

Authors:  Michael M Ward
Journal:  Arthritis Rheum       Date:  2004-08-15

4.  Validation of death certificate diagnosis for coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study.

Authors:  S A Coady; P D Sorlie; L S Cooper; A R Folsom; W D Rosamond; D E Conwill
Journal:  J Clin Epidemiol       Date:  2001-01       Impact factor: 6.437

5.  Mortality associated with systemic lupus erythematosus in France assessed by multiple-cause-of-death analysis.

Authors:  Guillemette Thomas; Julien Mancini; Noémie Jourde-Chiche; Gabrielle Sarlon; Zahir Amoura; Jean-Robert Harlé; Eric Jougla; Laurent Chiche
Journal:  Arthritis Rheumatol       Date:  2014-09       Impact factor: 10.995

6.  46-Year Trends in Systemic Lupus Erythematosus Mortality in the United States, 1968 to 2013: A Nationwide Population-Based Study.

Authors:  Eric Y Yen; Magda Shaheen; Jennifer M P Woo; Neil Mercer; Ning Li; Deborah K McCurdy; Arun Karlamangla; Ram R Singh
Journal:  Ann Intern Med       Date:  2017-10-31       Impact factor: 25.391

  6 in total
  51 in total

1.  Hacking systemic lupus erythematosus (SLE): outcomes of the Waterlupus hackathon.

Authors:  Francesca S Cardwell; Elijah Bisung; Ann E Clarke; Susan J Elliott
Journal:  Health Promot Chronic Dis Prev Can       Date:  2020-08       Impact factor: 3.240

2.  Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity.

Authors:  Takayuki Katsuyama; Hao Li; Denis Comte; George C Tsokos; Vaishali R Moulton
Journal:  J Clin Invest       Date:  2019-12-02       Impact factor: 14.808

3.  Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity.

Authors:  Lingyan Chen; Yong-Fei Wang; Lu Liu; Adrianna Bielowka; Rahell Ahmed; Huoru Zhang; Phil Tombleson; Amy L Roberts; Christopher A Odhams; Deborah S Cunninghame Graham; Xuejun Zhang; Wanling Yang; Timothy J Vyse; David L Morris
Journal:  Hum Mol Genet       Date:  2020-06-27       Impact factor: 6.150

4.  Exacerbating lupus nephritis following BPA exposure is associated with abnormal autophagy in MRL/lpr mice.

Authors:  Youdan Dong; Zeming Zhang; Hezuo Liu; Lihong Jia; Muting Qin; Xiaofei Wang
Journal:  Am J Transl Res       Date:  2020-02-15       Impact factor: 4.060

5.  Splicing factor SRSF1 controls T cell homeostasis and its decreased levels are linked to lymphopenia in systemic lupus erythematosus.

Authors:  Takayuki Katsuyama; Ignacio Juarez Martin-Delgado; Suzanne M Krishfield; Vasileios C Kyttaris; Vaishali R Moulton
Journal:  Rheumatology (Oxford)       Date:  2020-08-01       Impact factor: 7.580

6.  SLE mortality remains disproportionately high, despite improvements over the last decade.

Authors:  R R Singh; E Y Yen
Journal:  Lupus       Date:  2018-07-17       Impact factor: 2.911

7.  Splicing factor SRSF1 limits IFN-γ production via RhoH and ameliorates experimental nephritis.

Authors:  Takayuki Katsuyama; Hao Li; Suzanne M Krishfield; Vasileios C Kyttaris; Vaishali R Moulton
Journal:  Rheumatology (Oxford)       Date:  2021-01-05       Impact factor: 7.580

Review 8.  New therapeutic strategies in systemic lupus erythematosus management.

Authors:  Mariele Gatto; Margherita Zen; Luca Iaccarino; Andrea Doria
Journal:  Nat Rev Rheumatol       Date:  2019-01       Impact factor: 20.543

Review 9.  Leveraging Heterogeneity in Systemic Lupus Erythematosus for New Therapies.

Authors:  Marilyn E Allen; Violeta Rus; Gregory L Szeto
Journal:  Trends Mol Med       Date:  2020-10-09       Impact factor: 11.951

10.  Association of a Combination of Healthy Lifestyle Behaviors With Reduced Risk of Incident Systemic Lupus Erythematosus.

Authors:  May Y Choi; Jill Hahn; Susan Malspeis; Emma F Stevens; Elizabeth W Karlson; Jeffrey A Sparks; Kazuki Yoshida; Laura Kubzansky; Karen H Costenbader
Journal:  Arthritis Rheumatol       Date:  2022-01-11       Impact factor: 10.995

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