Julia Freckelton1, Darcy Holt2, Adina Borsaru2, StellaMay Gwini3, Daniel Croagh4,5, Gregory Moore4,6. 1. School of Clinical Sciences, Monash University, 246 Clayton Rd, Clayton, VIC, 3168, Australia. jmfreckelton@gmail.com. 2. Clinical Nutrition and Metabolism Unit, Monash Health, 246 Clayton Rd, Clayton, VIC, 3168, Australia. 3. Department of Epidemiology and Preventive Medicine, Monash University, 246 Clayton Rd, Clayton, VIC, 3168, Australia. 4. School of Clinical Sciences, Monash University, 246 Clayton Rd, Clayton, VIC, 3168, Australia. 5. Department of Surgery, Monash Health, 246 Clayton Rd, Clayton, VIC, 3168, Australia. 6. Department of Gastroenterology and Hepatology, Monash Health, 246 Clayton Rd, Clayton, VIC, 3168, Australia.
Abstract
BACKGROUND: Diverticular disease is a common, chronic inflammatory disease of the bowel. This study investigates the differences in body composition between patients with diverticular disease and those without. METHODS: Appropriate patients were identified using a search of the radiology database. Demographic and disease information was gathered using scanned medical records. Body composition analysis was performed at level L3 using single-slice computed tomography techniques. RESULTS: Two hundred seventy-one patients were included in this study: 83 controls, 93 with diverticulosis and 95 with diverticulitis. Diverticulitis and diverticulosis were associated with a significantly higher visceral fat area (VFA), than the control group (p < 0.001, p < 0.001). Diverticulitis and diverticulosis were associated with a significantly higher visceral fat area to subcutaneous fat area ratio (VFA:SCFA), than the control group (p = 0.005, p = 0.019). Only diverticulosis was associated with increased levels of extramyocellular fat, when compared to the control group (p = 0.001). CONCLUSION: Diverticular disease is associated with a higher amount and a higher proportion of visceral fat than seen in controls without diverticular disease.
BACKGROUND:Diverticular disease is a common, chronic inflammatory disease of the bowel. This study investigates the differences in body composition between patients with diverticular disease and those without. METHODS: Appropriate patients were identified using a search of the radiology database. Demographic and disease information was gathered using scanned medical records. Body composition analysis was performed at level L3 using single-slice computed tomography techniques. RESULTS: Two hundred seventy-one patients were included in this study: 83 controls, 93 with diverticulosis and 95 with diverticulitis. Diverticulitis and diverticulosis were associated with a significantly higher visceral fat area (VFA), than the control group (p < 0.001, p < 0.001). Diverticulitis and diverticulosis were associated with a significantly higher visceral fat area to subcutaneous fat area ratio (VFA:SCFA), than the control group (p = 0.005, p = 0.019). Only diverticulosis was associated with increased levels of extramyocellular fat, when compared to the control group (p = 0.001). CONCLUSION:Diverticular disease is associated with a higher amount and a higher proportion of visceral fat than seen in controls without diverticular disease.
Entities:
Keywords:
Body composition; Diverticulosis; Diverticulum; Extramyocellular fat; Visceral fat
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