| Literature DB >> 2967038 |
A De Volder1, A Bol, C Michel, M Cogneau, P Evrard, G Lyon, A M Goffinet.
Abstract
Brain glucose metabolism was measured in two children with early-onset Huntington's disease, using positron emission tomography with fluorodeoxyglucose (FDG) as the tracer. A marked (48%) hypometabolism was found at the level of the caudate nuclei, but other areas of the brain, particularly the cerebral cortex, were not significantly affected. Despite its different clinical presentation, Huntington's disease in children is characterized by brain metabolic alterations similar to those found in adult patients.Entities:
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Year: 1988 PMID： 2967038 DOI： 10.1016/s0387-7604(88)80046-9
Source DB: PubMed Journal: Brain Dev ISSN： 0387-7604 Impact factor: 1.961