Literature DB >> 2966993

Genetics of susceptibility to 6-aminonicotinamide-induced cleft palate in the mouse: studies in congenic and recombinant inbred strains.

J Karolyi1, R P Erickson, S Liu.   

Abstract

In a search for genetic differences in susceptibility to cleft palate, congenic and recombinant inbred strains of mice were treated with 6-aminonicotinamide or control injections. Of six loci tested, only the chromosome segment marked by N-acetyl transferase was found to affect susceptibility to 6-aminonicotinamide-induced cleft palate. This chromosome segment is known to affect glucocorticoid-induced cleft palate and phenytoin-induced cleft lip with or without cleft palate in these strains of mice.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 2966993     DOI： 10.1002/tera.1420370314

Source DB:  PubMed          Journal:  Teratology        ISSN： 0040-3709


  4 in total

1.  Long-range enhancers regulating Myc expression are required for normal facial morphogenesis.

Authors:  Veli Vural Uslu; Massimo Petretich; Sandra Ruf; Katja Langenfeld; Nuno A Fonseca; John C Marioni; François Spitz
Journal:  Nat Genet       Date:  2014-05-25       Impact factor: 38.330

2.  Major effects on teratogen-induced facial clefting in mice determined by a single genetic region.

Authors:  J Karolyi; R P Erickson; S Liu; L Killewald
Journal:  Genetics       Date:  1990-09       Impact factor: 4.562

3.  Genome scan for teratogen-induced clefting susceptibility loci in the mouse: evidence of both allelic and locus heterogeneity distinguishing cleft lip and cleft palate.

Authors:  S R Diehl; R P Erickson
Journal:  Proc Natl Acad Sci U S A       Date:  1997-05-13       Impact factor: 11.205

4.  Effect of the dam strain on the spontaneous incidence of cleft lip and palate and intrauterine growth of CL/Fr mouse fetuses.

Authors:  K Nonaka; Y Sasaki; D A Martin; M Nakata
Journal:  J Assist Reprod Genet       Date:  1995-08       Impact factor: 3.412
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.