Literature DB >> 29669859

Anti-cancer therapy: senescence is the new black.

Rodrigo Leite de Oliveira1, Rene Bernards1.   

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Year:  2018        PMID： 29669859      PMCID： PMC5978283          DOI： 10.15252/embj.201899386

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


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  12 in total

1.  Constitutive HER2 signaling promotes breast cancer metastasis through cellular senescence.

Authors:  Pier Davide Angelini; Mariano F Zacarias Fluck; Kim Pedersen; Josep Lluís Parra-Palau; Marc Guiu; Cristina Bernadó Morales; Rocio Vicario; Antonio Luque-García; Nerea Peiró Navalpotro; Jordi Giralt; Francesc Canals; Roger R Gomis; Josep Tabernero; José Baselga; Josep Villanueva; Joaquín Arribas
Journal:  Cancer Res       Date:  2013-01-01       Impact factor: 12.701

2.  Unmasking Transcriptional Heterogeneity in Senescent Cells.

Authors:  Alejandra Hernandez-Segura; Tristan V de Jong; Simon Melov; Victor Guryev; Judith Campisi; Marco Demaria
Journal:  Curr Biol       Date:  2017-08-30       Impact factor: 10.834

3.  High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer.

Authors:  Liqin Wang; Rodrigo Leite de Oliveira; Cun Wang; João M Fernandes Neto; Sara Mainardi; Bastiaan Evers; Cor Lieftink; Ben Morris; Fleur Jochems; Lisa Willemsen; Roderick L Beijersbergen; René Bernards
Journal:  Cell Rep       Date:  2017-10-17       Impact factor: 9.423

Review 4.  Cellular senescence: Immunosurveillance and future immunotherapy.

Authors:  Dominick G A Burton; Alexandra Stolzing
Journal:  Ageing Res Rev       Date:  2018-02-07       Impact factor: 10.895

5.  Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma.

Authors:  Chong Sun; Liqin Wang; Sidong Huang; Guus J J E Heynen; Anirudh Prahallad; Caroline Robert; John Haanen; Christian Blank; Jelle Wesseling; Stefan M Willems; Davide Zecchin; Sebastijan Hobor; Prashanth K Bajpe; Cor Lieftink; Christina Mateus; Stephan Vagner; Wipawadee Grernrum; Ingrid Hofland; Andreas Schlicker; Lodewyk F A Wessels; Roderick L Beijersbergen; Alberto Bardelli; Federica Di Nicolantonio; Alexander M M Eggermont; Rene Bernards
Journal:  Nature       Date:  2014-03-26       Impact factor: 49.962

Review 6.  Therapy-induced senescence in cancer.

Authors:  Jonathan A Ewald; Joshua A Desotelle; George Wilding; David F Jarrard
Journal:  J Natl Cancer Inst       Date:  2010-09-21       Impact factor: 13.506

7.  Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.

Authors:  Jianhui Chang; Yingying Wang; Lijian Shao; Remi-Martin Laberge; Marco Demaria; Judith Campisi; Krishnamurthy Janakiraman; Norman E Sharpless; Sheng Ding; Wei Feng; Yi Luo; Xiaoyan Wang; Nukhet Aykin-Burns; Kimberly Krager; Usha Ponnappan; Martin Hauer-Jensen; Aimin Meng; Daohong Zhou
Journal:  Nat Med       Date:  2015-12-14       Impact factor: 53.440

Review 8.  The senescence-associated secretory phenotype: the dark side of tumor suppression.

Authors:  Jean-Philippe Coppé; Pierre-Yves Desprez; Ana Krtolica; Judith Campisi
Journal:  Annu Rev Pathol       Date:  2010       Impact factor: 23.472

9.  Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence.

Authors:  Masashi Narita; Sabrina Nũnez; Edith Heard; Masako Narita; Athena W Lin; Stephen A Hearn; David L Spector; Gregory J Hannon; Scott W Lowe
Journal:  Cell       Date:  2003-06-13       Impact factor: 41.582

Review 10.  Targeting the RB-E2F pathway in breast cancer.

Authors:  J Johnson; B Thijssen; U McDermott; M Garnett; L F A Wessels; R Bernards
Journal:  Oncogene       Date:  2016-02-29       Impact factor: 9.867
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  9 in total

Review 1.  Targeting tumor cell senescence and polyploidy as potential therapeutic strategies.

Authors:  Tareq Saleh; Valerie J Carpenter; Sarah Bloukh; David A Gewirtz
Journal:  Semin Cancer Biol       Date:  2020-12-20       Impact factor: 17.012

Review 2.  Functional heterogeneity in senescence.

Authors:  Kristina Kirschner; Nattaphong Rattanavirotkul; Megan F Quince; Tamir Chandra
Journal:  Biochem Soc Trans       Date:  2020-06-30       Impact factor: 5.407

Review 3.  Molecular Mechanisms of Senescence and Implications for the Treatment of Myeloid Malignancies.

Authors:  Philipp Ernst; Florian H Heidel
Journal:  Cancers (Basel)       Date:  2021-02-04       Impact factor: 6.639

Review 4.  Cellular Senescence and Ageing: Mechanisms and Interventions.

Authors:  Andreas Mylonas; Ana O'Loghlen
Journal:  Front Aging       Date:  2022-03-29

5.  Nutritional Niches of Cancer Therapy-Induced Senescent Cells.

Authors:  Àngela Llop-Hernández; Sara Verdura; Elisabet Cuyàs; Javier A Menendez
Journal:  Nutrients       Date:  2022-09-02       Impact factor: 6.706

6.  Identification of Autophagy-Related Genes as Targets for Senescence Induction Using a Customizable CRISPR-Based Suicide Switch Screen.

Authors:  Arnout Schepers; Fleur Jochems; Cor Lieftink; Liqin Wang; Ziva Pogacar; Rodrigo Leite de Oliveira; Giulia De Conti; Roderick L Beijersbergen; Rene Bernards
Journal:  Mol Cancer Res       Date:  2021-06-22       Impact factor: 5.852

7.  BAP18 is involved in upregulation of CCND1/2 transcription to promote cell growth in oral squamous cell carcinoma.

Authors:  Xue Wang; Chunyu Wang; Guangqi Yan; Yuanyuan Kang; Ge Sun; Shengli Wang; Renlong Zou; Hongmiao Sun; Kai Zeng; Huijuan Song; Wei Liu; Ning Sun; Wensu Liu; Yue Zhao
Journal:  EBioMedicine       Date:  2020-02-27       Impact factor: 8.143

8.  Clearance of therapy-induced senescent tumor cells by the senolytic ABT-263 via interference with BCL-XL -BAX interaction.

Authors:  Tareq Saleh; Valerie J Carpenter; Liliya Tyutyunyk-Massey; Graeme Murray; Joel D Leverson; Andrew J Souers; Moureq R Alotaibi; Anthony C Faber; Jason Reed; Hisashi Harada; David A Gewirtz
Journal:  Mol Oncol       Date:  2020-08-05       Impact factor: 6.603

9.  Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy.

Authors:  Pataje G Prasanna; Deborah E Citrin; Jeffrey Hildesheim; Mansoor M Ahmed; Sundar Venkatachalam; Gabriela Riscuta; Dan Xi; Guangrong Zheng; Jan van Deursen; Jorg Goronzy; Stephen J Kron; Mitchell S Anscher; Norman E Sharpless; Judith Campisi; Stephen L Brown; Laura J Niedernhofer; Ana O'Loghlen; Alexandros G Georgakilas; Francois Paris; David Gius; David A Gewirtz; Clemens A Schmitt; Mohamed E Abazeed; James L Kirkland; Ann Richmond; Paul B Romesser; Scott W Lowe; Jesus Gil; Marc S Mendonca; Sandeep Burma; Daohong Zhou; C Norman Coleman
Journal:  J Natl Cancer Inst       Date:  2021-10-01       Impact factor: 11.816
  9 in total

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