Literature DB >> 29669852

Cholesterol, cancer, and rebooting a treatment for athlete's foot.

Ngee Kiat Chua1, Hudson W Coates1, Andrew J Brown2.   

Abstract

A key enzyme in cholesterol synthesis is placed firmly on the oncogenic map and demonstrated to be a potential therapeutic target in liver cancer by repurposing a common antifungal agent (Liu et al, this issue).
Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

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Year:  2018        PMID： 29669852     DOI： 10.1126/scitranslmed.aat3741

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN： 1946-6234            Impact factor:   17.956


  7 in total

1.  AGR2-induced cholesterol synthesis drives lovastatin resistance that is overcome by combination therapy with allicin.

Authors:  Nan Sheng; Yun-Qiu Wang; Cun-Fu Wang; Meng-Qi Jia; Huan-Min Niu; Qi-Qi Lu; Ya-Nan Wang; Dan Feng; Xiao-Xue Zheng; Hui-Qing Yuan
Journal:  Acta Pharmacol Sin       Date:  2022-04-22       Impact factor: 6.150

2.  Cholesterol homeostasis and cancer: a new perspective on the low-density lipoprotein receptor.

Authors:  Jia Gu; Neng Zhu; Hong-Fang Li; Tan-Jun Zhao; Chan-Juan Zhang; Duan-Fang Liao; Li Qin
Journal:  Cell Oncol (Dordr)       Date:  2022-07-22       Impact factor: 7.051

3.  Targeting the transcription factor receptor LXR to treat clear cell renal cell carcinoma: agonist or inverse agonist?

Authors:  Guangzhen Wu; Qinglian Wang; Yingkun Xu; Jianyi Li; Hongge Zhang; Guanghui Qi; Qinghua Xia
Journal:  Cell Death Dis       Date:  2019-05-28       Impact factor: 8.469

Review 4.  The shape of human squalene epoxidase expands the arsenal against cancer.

Authors:  Andrew J Brown; Ngee Kiat Chua; Nieng Yan
Journal:  Nat Commun       Date:  2019-02-21       Impact factor: 14.919

5.  Chronic Disruption of the Late Cholesterol Synthesis Leads to Female-Prevalent Liver Cancer.

Authors:  Kaja Blagotinšek Cokan; Žiga Urlep; Gregor Lorbek; Madlen Matz-Soja; Cene Skubic; Martina Perše; Jera Jeruc; Peter Juvan; Tadeja Režen; Damjana Rozman
Journal:  Cancers (Basel)       Date:  2020-11-09       Impact factor: 6.639

Review 6.  Role of Cholesterol and Lipid Rafts in Cancer Signaling: A Promising Therapeutic Opportunity?

Authors:  Rosa Vona; Elisabetta Iessi; Paola Matarrese
Journal:  Front Cell Dev Biol       Date:  2021-03-19

Review 7.  Role of de novo cholesterol synthesis enzymes in cancer.

Authors:  Jie Yang; Lihua Wang; Renbing Jia
Journal:  J Cancer       Date:  2020-01-17       Impact factor: 4.207
  7 in total

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