Literature DB >> 29669754

Ectopic Lck expression in CLL demarcates intratumoral subpopulations with aberrant B-cell receptor signaling.

Efthymia Theofani1,2, Spyridon Alexis2, Paul Costeas3, Christos Andriopoulos2, Georgia Feleskoura2, Panagiotis Zikos4, Anthi Aktypi5, Alexandros Spyridonidis2, Konstantina Nika1.   

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Year:  2018        PMID： 29669754      PMCID： PMC5916004          DOI： 10.1182/bloodadvances.2017015321

Source DB:  PubMed          Journal:  Blood Adv        ISSN： 2473-9529


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  24 in total

1.  Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection.

Authors:  Andrew Burchat; David W Borhani; David J Calderwood; Gavin C Hirst; Biqin Li; Robert F Stachlewitz
Journal:  Bioorg Med Chem Lett       Date:  2005-10-10       Impact factor: 2.823

2.  CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells.

Authors:  Rajendra N Damle; Sonal Temburni; Carlo Calissano; Sophia Yancopoulos; Taraneh Banapour; Cristina Sison; Steven L Allen; Kanti R Rai; Nicholas Chiorazzi
Journal:  Blood       Date:  2007-08-07       Impact factor: 22.113

3.  Evolution and impact of subclonal mutations in chronic lymphocytic leukemia.

Authors:  Dan A Landau; Scott L Carter; Petar Stojanov; Aaron McKenna; Kristen Stevenson; Michael S Lawrence; Carrie Sougnez; Chip Stewart; Andrey Sivachenko; Lili Wang; Youzhong Wan; Wandi Zhang; Sachet A Shukla; Alexander Vartanov; Stacey M Fernandes; Gordon Saksena; Kristian Cibulskis; Bethany Tesar; Stacey Gabriel; Nir Hacohen; Matthew Meyerson; Eric S Lander; Donna Neuberg; Jennifer R Brown; Gad Getz; Catherine J Wu
Journal:  Cell       Date:  2013-02-14       Impact factor: 41.582

4.  CD69 is independently prognostic in chronic lymphocytic leukemia: a comprehensive clinical and biological profiling study.

Authors:  Giovanni Del Poeta; Maria Ilaria Del Principe; Antonella Zucchetto; Fabrizio Luciano; Francesco Buccisano; Francesca Maria Rossi; Antonio Bruno; Annalisa Biagi; Pietro Bulian; Luca Maurillo; Benedetta Neri; Riccardo Bomben; Cristina Simotti; Angela Maria Coletta; Michele Dal Bo; Paolo de Fabritiis; Adriano Venditti; Valter Gattei; Sergio Amadori
Journal:  Haematologica       Date:  2011-10-11       Impact factor: 9.941

5.  Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy.

Authors:  Marta Muzio; Benedetta Apollonio; Cristina Scielzo; Michela Frenquelli; Irene Vandoni; Vassiliki Boussiotis; Federico Caligaris-Cappio; Paolo Ghia
Journal:  Blood       Date:  2008-02-21       Impact factor: 22.113

6.  Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines.

Authors:  Michael Hallek; Bruce D Cheson; Daniel Catovsky; Federico Caligaris-Cappio; Guillaume Dighiero; Hartmut Döhner; Peter Hillmen; Michael J Keating; Emili Montserrat; Kanti R Rai; Thomas J Kipps
Journal:  Blood       Date:  2008-01-23       Impact factor: 22.113

7.  Targeting B-cell anergy in chronic lymphocytic leukemia.

Authors:  Benedetta Apollonio; Cristina Scielzo; Maria Teresa Sabrina Bertilaccio; Elisa Ten Hacken; Lydia Scarfò; Pamela Ranghetti; Freda Stevenson; Graham Packham; Paolo Ghia; Marta Muzio; Federico Caligaris-Cappio
Journal:  Blood       Date:  2013-03-04       Impact factor: 22.113

8.  Constitutively active Lck kinase in T cells drives antigen receptor signal transduction.

Authors:  Konstantina Nika; Cristiana Soldani; Mogjiborahman Salek; Wolfgang Paster; Adrian Gray; Ruth Etzensperger; Lars Fugger; Paolo Polzella; Vincenzo Cerundolo; Omer Dushek; Thomas Höfer; Antonella Viola; Oreste Acuto
Journal:  Immunity       Date:  2010-06-11       Impact factor: 31.745

9.  Small molecule inhibition of Csk alters affinity recognition by T cells.

Authors:  Boryana N Manz; Ying Xim Tan; Adam H Courtney; Florentine Rutaganira; Ed Palmer; Kevan M Shokat; Arthur Weiss
Journal:  Elife       Date:  2015-08-24       Impact factor: 8.140

10.  NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia.

Authors:  Melanie Märklin; Jonas S Heitmann; Alexander R Fuchs; Felicia M Truckenmüller; Michael Gutknecht; Stefanie Bugl; Sebastian J Saur; Juliane Lazarus; Ursula Kohlhofer; Leticia Quintanilla-Martinez; Hans-Georg Rammensee; Helmut R Salih; Hans-Georg Kopp; Michael Haap; Andreas Kirschniak; Lothar Kanz; Anjana Rao; Stefan Wirths; Martin R Müller
Journal:  Nat Commun       Date:  2017-10-02       Impact factor: 14.919
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  1 in total

1.  Genetic Loss of LCK Kinase Leads to Acceleration of Chronic Lymphocytic Leukemia.

Authors:  Melanie Märklin; Alexander R Fuchs; Claudia Tandler; Jonas S Heitmann; Helmut R Salih; Joseph Kauer; Leticia Quintanilla-Martinez; Stefan Wirths; Hans-Georg Kopp; Martin R Müller
Journal:  Front Immunol       Date:  2020-09-02       Impact factor: 7.561
  1 in total

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