| Literature DB >> 29669244 |
Melissa A Meyer1, David G DeNardo2.
Abstract
T cell checkpoint blockades can produce durable clinical responses, but only some patients and cancer types respond. In this issue of Immunity, Li et al. (2018) show B7S1-B7S1R signaling additionally regulates CD8+ T cell responses by working with the PD1-PDL1 checkpoint to block anti-tumor immunity.Entities:
Mesh:
Year: 2018 PMID: 29669244 DOI: 10.1016/j.immuni.2018.03.029
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745