Literature DB >> 29668550

Pediatric Chronic Myeloid Leukemia Presenting With Extreme Thrombocytosis Simulating Essential Thrombocythemia.

Jessica L Boklan1, Alexandra M Walsh1, Michelina C de la Maza1, Leon L Su2, Francisco A Nizzi2, Kristian T Schafernak2.   

Abstract

A 10-year-old boy presented with spontaneous bruising and was found to have extreme thrombocytosis without neutrophilia/shift to immaturity, basophilia or eosinophilia. While the peripheral blood and bone marrow findings initially suggested essential thrombocythemia, BCR-ABL1 translocation was detected and chronic myeloid leukemia, chronic phase, was diagnosed. Apheresis for platelet depletion was performed as a bridge given the delayed effects of medical therapy.

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Year:  2018        PMID: 29668550     DOI: 10.1097/MPH.0000000000001154

Source DB:  PubMed          Journal:  J Pediatr Hematol Oncol        ISSN: 1077-4114            Impact factor:   1.289


  1 in total

Review 1.  Clinical Features and Outcomes of Patients With Chronic Myeloid Leukemia Presenting With Isolated Thrombocytosis: A Systematic Review and a Case From Our Institution.

Authors:  Dawood Findakly; Waqas Arslan
Journal:  Cureus       Date:  2020-06-23
  1 in total

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