Chih-Wei Wang1,2, Yueng-Hsiang Chu3, Deng-Yiv Chiu4, Nieh Shin5, Hsian-He Hsu1,2, Jih-Chin Lee3, Chun-Jung Juan1,2. 1. 1 Department of Radiology, National Defense Medical Center, Taipei, Taiwan, Republic of China. 2. 2 Department of Radiology, Tri-Service General Hospital, 325, Sec 2, Cheng-Kong Rd, Neihu, Taipei, Taiwan, Republic of China. 3. 3 Department of Otolaryngology-Head & Neck Surgery, National Defense Medical Center and Tri-Service General Hospital, Taipei, Taiwan, Republic of China. 4. 4 Department of Information Management, Chung-Hua University, Hsinchu, Taiwan, Republic of China. 5. 5 Department of Pathology, Graduate Institute of Pathology and Parasitology, National Defense Medical Center, Taipei, Taiwan, Republic of China.
Abstract
OBJECTIVE: The objective of this article is to propose a Warthin tumor (WT) score to distinguish WTs from other parotid tumors. MATERIALS AND METHODS: The study included 78 patients with 92 histologically proven parotid tumors, including 42 WTs, 30 pleomorphic adenomas (PMAs), and 20 carcinomas. Echo-planar DW images were acquired. The WT score, which comprised the mean apparent diffusion coefficient (ADCM) and the SD of the ADC (ADCSD) of tumors, patient age, and patient sex, was used to predict WTs. The diagnostic performance of the WT score was evaluated using ROC analyses. Statistical significance was denoted by p < 0.05. RESULTS: With the use of optimized criteria, including an ADCM less than or equal to 1.016 × 10-3 mm2/s (WT score, 1), an ADCSD less than or equal to 0.1171 × 10-3 mm2/s (WT score, 1), patient age older than 49 years (WT score, 1), and male sex (WT score, 1), a WT score greater than 2 had a sensitivity, specificity, positive negative value, negative predictive value, and accuracy of 85.7%, 100.0%, 100.0%, 89.3%, and 93.4%, respectively. CONCLUSION: The WT score allows parotid WTs to be distinguished from PMAs and carcinomas with high accuracy.
OBJECTIVE: The objective of this article is to propose a Warthin tumor (WT) score to distinguish WTs from other parotid tumors. MATERIALS AND METHODS: The study included 78 patients with 92 histologically proven parotid tumors, including 42 WTs, 30 pleomorphic adenomas (PMAs), and 20 carcinomas. Echo-planar DW images were acquired. The WT score, which comprised the mean apparent diffusion coefficient (ADCM) and the SD of the ADC (ADCSD) of tumors, patient age, and patient sex, was used to predict WTs. The diagnostic performance of the WT score was evaluated using ROC analyses. Statistical significance was denoted by p < 0.05. RESULTS: With the use of optimized criteria, including an ADCM less than or equal to 1.016 × 10-3 mm2/s (WT score, 1), an ADCSD less than or equal to 0.1171 × 10-3 mm2/s (WT score, 1), patient age older than 49 years (WT score, 1), and male sex (WT score, 1), a WT score greater than 2 had a sensitivity, specificity, positive negative value, negative predictive value, and accuracy of 85.7%, 100.0%, 100.0%, 89.3%, and 93.4%, respectively. CONCLUSION: The WT score allows parotid WTs to be distinguished from PMAs and carcinomas with high accuracy.
Authors: Fakih Cihat Eravcı; Deniz Sözmen Cılız; Kürşat Murat Özcan; Mustafa Çolak; Mehtap Çavuşoğlu; Süleyman Emre Karakurt; Mehmet Fatih Karakuş Journal: Turk Arch Otorhinolaryngol Date: 2020-09-01