| Literature DB >> 29667206 |
Rohit Sharma1, Larissa Costa Santos1, Robson A da Silva2, Caroline V Gonçalves2, Stéfano de Melo Calado2, Denisar P Santos2, Josana P de Andrade de Melo3, Rita de Cássia Pontello Rampazzo4, Luciana Requião4, Marco A Krieger4,5, Manoel Barral-Netto1,6, Camila I de Oliveira1,6.
Abstract
Reports of arboviral transmission via blood transfusion may be a cause of concern among asymptomatic infected donors. This study evaluated the presence of arboviruses in donated blood products during the 2016 outbreak in Vitória da Conquista (Bahia-Brazil). Serum samples (n = 676) were screened for ZIKV, CHIKV, and the four DENV serotypes using a one-step reverse transcriptase-based Real-Time Polymerase Chain Reaction (RT-PCR). No samples tested positive for any of the targets, whereas positive controls performed as expected. The results suggest a low risk of arboviral transmission via transfusion of blood products in the endemic area studied during the 2016 outbreak.Entities:
Keywords: NAT; ZIKV; transfusion
Mesh：
Year: 2018 PMID： 29667206 DOI： 10.1002/jmv.25193
Source DB: PubMed Journal: J Med Virol ISSN： 0146-6615 Impact factor: 2.327