Literature DB >> 29666690

Small-Cell Neuroendocrine Carcinoma of the Cervix Masquerading as a Cervical Fibroid: Report of a rare entity.

Mukta Pujani1, Kanika Singh1, Varsha Chauhan1, Raina Chawla2, Rashmi Ahuja2.   

Abstract

Primary neuroendocrine tumours of the cervix are extremely rare, with an incidence of only 0.5-1%; as such, these entities can present a clinical and diagnostic challenge. Small-cell neuroendocrine carcinomas of the cervix are highly aggressive tumours that have a tendency to metastasise. We report a 44-year-old woman who presented to the Gynaecology Clinic of the Employees State Insurance Corporation Medical College & Hospital, Faridabad, India, in 2016 with menorrhagia. Based on a clinical examination, she was provisionally diagnosed with a cervical fibroid. However, a biopsy revealed features of a small-cell neuroendocrine carcinoma of the cervix which was subsequently confirmed via immunohistochemistry. An accurate diagnosis of a neuroendocrine carcinoma is vital as it forms the basis for treatment decisions as well as informing predictions for long-term survival.

Entities:  

Keywords:  Case Report; Cervix; Fibroid Tumor; India; Menorrhagia; Neuroendocrine Tumors; Small Cell Carcinoma

Mesh:

Year:  2018        PMID: 29666690      PMCID: PMC5892798          DOI: 10.18295/squmj.2018.18.01.017

Source DB:  PubMed          Journal:  Sultan Qaboos Univ Med J        ISSN: 2075-051X


  10 in total

Review 1.  FDG-PET/CT in lung cancer: an update.

Authors:  Richard P Baum; Cyprian Świętaszczyk; Vikas Prasad
Journal:  Front Radiat Ther Oncol       Date:  2009-11-24

Review 2.  An Update of Neuroendocrine Tumors of the Female Reproductive System.

Authors:  Mehmet Kefeli; Alp Usubütün
Journal:  Turk Patoloji Derg       Date:  2015

Review 3.  Neuroendocrine tumors of the gynecologic tract: A Society of Gynecologic Oncology (SGO) clinical document.

Authors:  Ginger J Gardner; Diane Reidy-Lagunes; Paola A Gehrig
Journal:  Gynecol Oncol       Date:  2011-07       Impact factor: 5.482

Review 4.  The neuroendocrine system and its tumors: an overview.

Authors:  R A DeLellis
Journal:  Am J Clin Pathol       Date:  2001-06       Impact factor: 2.493

5.  Small-cell carcinoma of the cervix: fourteen years of experience at a single institution using a combined-modality regimen of involved-field irradiation and platinum-based combination chemotherapy.

Authors:  P J Hoskins; K D Swenerton; J A Pike; P Lim; C Aquino-Parsons; F Wong; N Lee
Journal:  J Clin Oncol       Date:  2003-09-15       Impact factor: 44.544

6.  Small-cell neuroendocrine carcinoma of the cervix. A human papillomavirus type 18-associated cancer.

Authors:  M H Stoler; S E Mills; D J Gersell; A N Walker
Journal:  Am J Surg Pathol       Date:  1991-01       Impact factor: 6.394

7.  Neuroendocrine Carcinoma of the Cervix: Review of a Series of Cases and Correlation With Outcome.

Authors:  Raji Ganesan; Lynn Hirschowitz; Philip Dawson; Sarah Askew; Philippa Pearmain; Peter W Jones; Kavita Singh; Kiong K Chan; Esther L Moss
Journal:  Int J Surg Pathol       Date:  2016-04-20       Impact factor: 1.271

8.  Incidence, mortality, and prognostic factors of small cell carcinoma of the cervix.

Authors:  Jergin Chen; O Kenneth Macdonald; David K Gaffney
Journal:  Obstet Gynecol       Date:  2008-06       Impact factor: 7.661

9.  Advanced small cell carcinoma of the uterine cervix treated by neoadjuvant chemotherapy with irinotecan and cisplatin followed by radical surgery.

Authors:  Kaei Nasu; Tomoko Hirakawa; Mamiko Okamoto; Masakazu Nishida; Chihiro Kiyoshima; Harunobu Matsumoto; Noriyuki Takai; Hisashi Narahara
Journal:  Rare Tumors       Date:  2011-03-30

10.  Metastatic uterine cancer looking as cervical fibroid in recurrent breast cancer woman: a case report.

Authors:  So Young Seo; Jin Yong Shin; Yong Il Ji
Journal:  Obstet Gynecol Sci       Date:  2017-09-18
  10 in total
  1 in total

1.  Re: Small-Cell Neuroendocrine Carcinoma of the Cervix Masquerading as a Cervical Fibroid: Report of a rare entity.

Authors:  Mahmood D Al-Mendalawi
Journal:  Sultan Qaboos Univ Med J       Date:  2018-09-09
  1 in total

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