Literature DB >> 29666533

Purple head broccoli (Brassica oleracea L. var. italica Plenck), a functional food crop for antioxidant and anticancer potential.

Ashun Chaudhary1,2, Sonika Choudhary3, Upendra Sharma2, Adarsh Pal Vig1, Bikram Singh2, Saroj Arora1.   

Abstract

Natural foods are used in many folks and household treatments and have immense potential to treat a serious complication and health benefits, in addition to the basic nutritional values. These food products improve health, delay the aging process, increase life expectancy, and possibly prevent chronic diseases. Purple head Brassica oleracea L. var. italica Plenck is one of such foods and in current studies was explored for chemical compounds at different development stages by gas chromatography-mass spectrometry. Antioxidant potential was explored employing different assays like molybdate ion reduction, DPPH, superoxide anion radical scavenging and plasmid nicking assay. Inspired by antioxidant activity results, we further explored these extracts for antiproliferative potential by morphological changes, cell cycle analysis, measurement of intracellular peroxides and mitochondrial membrane potential changes. Current study provides the scientific basis for the use of broccoli as easily affordable potent functional food.

Entities:  

Keywords:  Antioxidant assay; Apoptosis; Broccoli; Cell cycle; GC–MS; MTT; ROS

Year:  2018        PMID: 29666533      PMCID: PMC5897301          DOI: 10.1007/s13197-018-3095-0

Source DB:  PubMed          Journal:  J Food Sci Technol        ISSN: 0022-1155            Impact factor:   2.701


  27 in total

Review 1.  Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism.

Authors:  P Talalay; J W Fahey
Journal:  J Nutr       Date:  2001-11       Impact factor: 4.798

Review 2.  Pharmacological basis of traditional medicines and health supplements as curatives.

Authors:  Takeshi Miyata
Journal:  J Pharmacol Sci       Date:  2007-02-08       Impact factor: 3.337

Review 3.  Chemopreventive functions of isothiocyanates.

Authors:  Young-Sam Keum; Woo-Sik Jeong; Ah-Ng Tony Kong
Journal:  Drug News Perspect       Date:  2005-09

4.  Antioxidant property of an ethanol extract of the stem of Opuntia ficus-indica var. saboten.

Authors:  Jeong-Chae Lee; Hak-Ryul Kim; Ju Kim; Yong-Suk Jang
Journal:  J Agric Food Chem       Date:  2002-10-23       Impact factor: 5.279

Review 5.  Chemical and biological characterisation of nutraceutical compounds of broccoli.

Authors:  D A Moreno; M Carvajal; C López-Berenguer; C García-Viguera
Journal:  J Pharm Biomed Anal       Date:  2006-05-19       Impact factor: 3.935

6.  Analysis and Antioxidant Activity of Extracts from Broccoli (Brassica oleracea L.) Sprouts.

Authors:  Hae Won Jang; Joon-Kwan Moon; Takayuki Shibamoto
Journal:  J Agric Food Chem       Date:  2015-01-20       Impact factor: 5.279

7.  A triterpenediol from Boswellia serrata induces apoptosis through both the intrinsic and extrinsic apoptotic pathways in human leukemia HL-60 cells.

Authors:  Shashi Bhushan; Ajay Kumar; Fayaz Malik; Samar Singh Andotra; Vijay Kumar Sethi; Indu Pal Kaur; Subhash Chandra Taneja; Ghulam Nabi Qazi; Jaswant Singh
Journal:  Apoptosis       Date:  2007-10       Impact factor: 4.677

8.  Gossypol acetic acid induces apoptosis in RAW264.7 cells via a caspase-dependent mitochondrial signaling pathway.

Authors:  Sijun Deng; Hui Yuan; Jine Yi; Yin Lu; Qiang Wei; Chengzhi Guo; Jing Wu; Liyun Yuan; Zuping He
Journal:  J Vet Sci       Date:  2013-06-30       Impact factor: 1.672

9.  ROS-dependent antiproliferative effect of brassinin derivative homobrassinin in human colorectal cancer Caco2 cells.

Authors:  Martin Kello; David Drutovic; Martina Chripkova; Martina Pilatova; Mariana Budovska; Lucia Kulikova; Peter Urdzik; Jan Mojzis
Journal:  Molecules       Date:  2014-07-25       Impact factor: 4.411

10.  Selenium enrichment of broccoli sprout extract increases chemosensitivity and apoptosis of LNCaP prostate cancer cells.

Authors:  Rizky Abdulah; Ahmad Faried; Kenji Kobayashi; Chiho Yamazaki; Eka W Suradji; Kazuto Ito; Kazuhiro Suzuki; Masami Murakami; Hiroyuki Kuwano; Hiroshi Koyama
Journal:  BMC Cancer       Date:  2009-11-30       Impact factor: 4.430

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  2 in total

1.  Antiproliferative Effect of Bioaccessible Fractions of Four Brassicaceae Microgreens on Human Colon Cancer Cells Linked to Their Phytochemical Composition.

Authors:  Beatriz de la Fuente; Gabriel López-García; Vicent Máñez; Amparo Alegría; Reyes Barberá; Antonio Cilla
Journal:  Antioxidants (Basel)       Date:  2020-04-28

2.  Broccoli (Brassica oleracea L. var. italica) Sprouts as the Potential Food Source for Bioactive Properties: A Comprehensive Study on In Vitro Disease Models.

Authors:  Thanh Ninh Le; Hong Quang Luong; Hsin-Ping Li; Chiu-Hsia Chiu; Pao-Chuan Hsieh
Journal:  Foods       Date:  2019-10-30
  2 in total

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