Aliona Tsypes1, Max Owens2, Greg Hajcak3, Brandon E Gibb1. 1. Center for Affective Science, Binghamton University, Binghamton, NY, USA. 2. University of South Florida, St. Petersburg, FL, USA. 3. Florida State University, Tallahassee, FL, USA.
Abstract
BACKGROUND: A better understanding of the correlates of nonsuicidal self-injury (NSSI) in children is important for the identification and prevention of future suicide risk. However, although abnormalities in reward responsiveness might constitute one potential transdiagnostic mechanism of risk for NSSI, no studies have examined initial response to reward in children with a history of NSSI. The goal of the present study was to address this important gap in the literature. To objectively assess initial response to reward, we utilized the feedback negativity (FN) event-related potential, a well-established psychophysiological marker of reward responsiveness. METHODS: Participants were 57 children (19 with a history of NSSI and 38 demographically matched controls) between the ages of 7 and 11. Diagnostic interviews were used to assess for current and past DSM-IV mood and anxiety diagnoses and NSSI history. Children also completed a guessing task, during which continuous electroencephalography was recorded. RESULTS: Children with a history of NSSI exhibited significantly more negative ΔFN (i.e., FN to losses minus FN to gains) than children without NSSI. These findings appeared to be at least partially independent of children's history of psychopathology and current symptoms, suggesting their specificity to NSSI. CONCLUSIONS: These results provide initial evidence for heightened neural initial reward responsiveness to losses versus rewards in children with a history of NSSI. Pending replications and longitudinal studies, the ΔFN might represent a psychophysiological marker of risk for self-harm.
BACKGROUND: A better understanding of the correlates of nonsuicidal self-injury (NSSI) in children is important for the identification and prevention of future suicide risk. However, although abnormalities in reward responsiveness might constitute one potential transdiagnostic mechanism of risk for NSSI, no studies have examined initial response to reward in children with a history of NSSI. The goal of the present study was to address this important gap in the literature. To objectively assess initial response to reward, we utilized the feedback negativity (FN) event-related potential, a well-established psychophysiological marker of reward responsiveness. METHODS:Participants were 57 children (19 with a history of NSSI and 38 demographically matched controls) between the ages of 7 and 11. Diagnostic interviews were used to assess for current and past DSM-IV mood and anxiety diagnoses and NSSI history. Children also completed a guessing task, during which continuous electroencephalography was recorded. RESULTS:Children with a history of NSSI exhibited significantly more negative ΔFN (i.e., FN to losses minus FN to gains) than children without NSSI. These findings appeared to be at least partially independent of children's history of psychopathology and current symptoms, suggesting their specificity to NSSI. CONCLUSIONS: These results provide initial evidence for heightened neural initial reward responsiveness to losses versus rewards in children with a history of NSSI. Pending replications and longitudinal studies, the ΔFN might represent a psychophysiological marker of risk for self-harm.
Authors: Daniel Vega; Pablo Ripollés; Àngel Soto; Rafael Torrubia; Joan Ribas; Jose Antonio Monreal; Juan Carlos Pascual; Raymond Salvador; Edith Pomarol-Clotet; Antoni Rodríguez-Fornells; Josep Marco-Pallarés Journal: Brain Imaging Behav Date: 2018-02 Impact factor: 3.978
Authors: Victoria M Sparrow-Downes; Sara Trincao-Batra; Paula Cloutier; Amanda R Helleman; Mina Salamatmanesh; William Gardner; Anton Baksh; Rishi Kapur; Nicole Sheridan; Sinthuja Suntharalingam; Lisa Currie; Liam D Carrie; Arthur Hamilton; Kathleen Pajer Journal: BMC Psychiatry Date: 2022-05-04 Impact factor: 3.630