Yale Tung-Chen1, Miguel-Ángel Arnau2. 1. a Emergency Department , Hospital Universitario La Paz , Madrid , Spain. 2. b Cardiology Department , Hospital Universitario y Politécnico La Fe , Valencia , Spain.
Abstract
BACKGROUND: Congestive heart failure (CHF) is a very common condition, especially in the elderly, characterized by dyspnea, orthopnea, nocturnal paroxysmal dyspnea, and peripheral edema. CLINICAL PRESENTATION AND INTERVENTION: We report the case of a 76-year-old with CHF symptoms for the last 3 months. The ECG and transthoracic echocardiogram were suggestive of CHF due to amyloid cardiomyopathy. After cardiac MRI, a positive Congo red staining of subcutaneous fat aspiration and a negative genetic testing for mutant transthyretin, senile amyloid cardiomyopathy (ATTRw) was expected. CONCLUSION: Cardiac amyloidosis is remarkably underdiagnosed. Mostly, the treatment is supportive and differs from other typical causes of CHF, and thus, a high index of suspicion is required.
BACKGROUND:Congestive heart failure (CHF) is a very common condition, especially in the elderly, characterized by dyspnea, orthopnea, nocturnal paroxysmal dyspnea, and peripheral edema. CLINICAL PRESENTATION AND INTERVENTION: We report the case of a 76-year-old with CHF symptoms for the last 3 months. The ECG and transthoracic echocardiogram were suggestive of CHF due to amyloid cardiomyopathy. After cardiac MRI, a positive Congo red staining of subcutaneous fat aspiration and a negative genetic testing for mutant transthyretin, senile amyloid cardiomyopathy (ATTRw) was expected. CONCLUSION:Cardiac amyloidosis is remarkably underdiagnosed. Mostly, the treatment is supportive and differs from other typical causes of CHF, and thus, a high index of suspicion is required.