Literature DB >> 29662361

Testicular volume discrepancy is associated with decreased semen quality in infertile Japanese males with varicoceles.

Akira Komiya1, Akihiko Watanabe1, Yoko Kawauchi1, Hideki Fuse1.   

Abstract

Purpose: We retrospectively reviewed infertile Japanese males for testicular volume discrepancies (D) and semen parameters to evaluate whether left grade II-III varicoceles (V) cause testicular damage.
Methods: Seventy-seven patients who had idiopathic male infertility and 88 who had V without other causes of infertility were examined. We excluded cases of azoospermia. Testicular volume was measured using a punched-out orchidometer. D was defined as a size difference of at least 3 ml. The frequency of D was compared between the patients with and without V. The semen parameters were reviewed in association with D and V.
Results: The mean left and right testicular volumes were 19.4 and 20.1 ml, respectively (p < 0.001). D with a smaller left testis was more common in V+ cases than in V- cases (26.1 vs. 13.0%, p = 0.0351). The sperm count and motility were also significantly lower (p = 0.0213 and p = 0.0217, respectively) in the D+ patients with a smaller left testicular volume. Conclusions: In the patients with V, D was more common than in those without V. The semen parameters were worse if D was present in the patients with V. These results indicated that V could induce testicular atrophy and negatively affect semen quality. Therefore, the ipsilateral reduced testicular volume is considered to be a sign of persisting testicular damage by V.

Entities:  

Keywords:  Male infertility; Semen parameter; Sperm count; Sperm motility; Varicocele

Year:  2012        PMID: 29662361      PMCID: PMC5892992          DOI: 10.1007/s12522-011-0118-1

Source DB:  PubMed          Journal:  Reprod Med Biol        ISSN: 1445-5781


  24 in total

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2.  Predictive parameters of successful varicocele repair.

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3.  Predictors of improved seminal characteristics by varicocele repair.

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Authors:  S J Skoog; K P Roberts; M Goldstein; J L Pryor
Journal:  Pediatrics       Date:  1997-07       Impact factor: 7.124

Review 5.  Pathophysiology of varicoceles in male infertility.

Authors:  C K Naughton; A K Nangia; A Agarwal
Journal:  Hum Reprod Update       Date:  2001 Sep-Oct       Impact factor: 15.610

6.  Testicular volume assessment in the adolescent with a varicocele.

Authors:  R A Costabile; S Skoog; M Radowich
Journal:  J Urol       Date:  1992-05       Impact factor: 7.450

7.  Prevalence of testicular size discrepancy in infertile men with and without varicoceles.

Authors:  Sutchin R Patel; Mark Sigman
Journal:  Urology       Date:  2009-12-06       Impact factor: 2.649

8.  Significance of testicular size measurement in andrology. I. A new orchiometer and its clinical application.

Authors:  H Takihara; J Sakatoku; M Fujii; T Nasu; M J Cosentino; A T Cockett
Journal:  Fertil Steril       Date:  1983-06       Impact factor: 7.329

9.  Impact of varicocele on testicular volume in young men: significance of compensatory hypertrophy of contralateral testis.

Authors:  Ja Hyeon Ku; Hwancheol Son; Cheol Kwak; Sang Eun Lee; Nam Kyu Lee; Young Ho Park
Journal:  J Urol       Date:  2002-10       Impact factor: 7.450

10.  Sperm morphologic features as a prognostic factor in in vitro fertilization.

Authors:  T F Kruger; R Menkveld; F S Stander; C J Lombard; J P Van der Merwe; J A van Zyl; K Smith
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  1 in total

1.  Severe oligozoospermia in a patient with myxedema coma.

Authors:  Akira Komiya; Akihiko Watanabe; Yoko Kawauchi; Atsuko Takano; Hideki Fuse
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  1 in total

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