Literature DB >> 29662262

Treatment of endo-periodontal lesion using leukocyte-platelet-rich fibrin. A case report.

Pablo Betancourt1, Ricardo Elgueta1,2, Ramon Fuentes1.   

Abstract

CASE DESCRIPTION: The main objective of this paper was to report the clinical effectiveness of leukocyte- platelet- rich fibrin (L-PRF) in the treatment of a combined endo-periodontal lesion of an upper first premolar. CLINICAL
FINDINGS: The tooth had a profound abfraction on the vestibular aspect and presented no mobility but revealed a deep pocket measuring of 11 mm on the mesial vestibular aspect and 14 mm on the mesial palatine aspect. The three dimensional image analysis showed total bone loss in the mesial aspect and an extensively bone loss of the vestibular aspect of the vestibular root. TREATMENT AND OUTCOME: Endodontic treatment was performed and periodontal access surgery (surgical periodontal therapy) was done with the application of autologous L-PRF. Three month and 6 months after surgery, the cone beam computed tomography (CBCT) exams showed no bone regeneration in any aspect of the tooth. However, periodontal examination showed a significative improvement in the deepness of surcus. The mesial vestibular aspect had a deep pocket of 3 mm and 5 mm on the mesial palatine aspect showing a reduction in deepness of 8 mm and 9 mm, respectively. CLINICAL RELEVANCE: The actual treatment for teeth with bad prognosis is the extraction and replacement with implants. Even though implants are capable of restore function and aesthetic, the abuse of this approach have led to the loss of teeth that could be successfully treated with a less invasive technique. The prognosis of teeth with endoperiodontal lesion is poor but could be enhanced with regenerative therapies. Until now there are no clinical trials and just four case report about the treatment of these teeth with platelet rich fibrin.

Entities:  

Keywords:  Blood platelets; endodontics; fibrin; leukocytes; surgical procedures

Mesh:

Year:  2017        PMID: 29662262      PMCID: PMC5896727          DOI: 10.25100/cm.v43i4.2140

Source DB:  PubMed          Journal:  Colomb Med (Cali)        ISSN: 0120-8322


  19 in total

Review 1.  Diagnosis, prognosis and decision-making in the treatment of combined periodontal-endodontic lesions.

Authors:  Ilan Rotstein; James H S Simon
Journal:  Periodontol 2000       Date:  2004       Impact factor: 7.589

2.  Antimicrobial activity of platelet-leukocyte gel against Staphylococcus aureus.

Authors:  Dirk Jan F Moojen; Peter A M Everts; Rose-Minke Schure; Ed P Overdevest; André van Zundert; Johannes T A Knape; René M Castelein; Laura B Creemers; Wouter J A Dhert
Journal:  J Orthop Res       Date:  2008-03       Impact factor: 3.494

Review 3.  Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF).

Authors:  David M Dohan Ehrenfest; Lars Rasmusson; Tomas Albrektsson
Journal:  Trends Biotechnol       Date:  2009-01-31       Impact factor: 19.536

4.  Treatment of 3-wall intrabony defects in patients with chronic periodontitis with autologous platelet-rich fibrin: a randomized controlled clinical trial.

Authors:  Anuj Sharma; A R Pradeep
Journal:  J Periodontol       Date:  2011-04-05       Impact factor: 6.993

5.  Resection and Regeneration - A Novel Approach in Treating a Perio-endo Lesion.

Authors:  Vineetha Varughese; Jaideep Mahendra; Anchu Rachel Thomas; N Ambalavanan
Journal:  J Clin Diagn Res       Date:  2015-03-01

Review 6.  The structure and biological features of fibrinogen and fibrin.

Authors:  M W Mosesson; K R Siebenlist; D A Meh
Journal:  Ann N Y Acad Sci       Date:  2001       Impact factor: 5.691

7.  A comparative study of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) on the effect of proliferation and differentiation of rat osteoblasts in vitro.

Authors:  Ling He; Ye Lin; Xiulian Hu; Yu Zhang; Hui Wu
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2009-11

8.  The periodontal - endodontic continuum: A review.

Authors:  Raja Sunitha V; Pamela Emmadi; Ambalavanan Namasivayam; Ramakrishnan Thyegarajan; Vijayalakshmi Rajaraman
Journal:  J Conserv Dent       Date:  2008-04

9.  Platelet-rich fibrin promotes periodontal regeneration and enhances alveolar bone augmentation.

Authors:  Qi Li; Shuang Pan; Smit J Dangaria; Gokul Gopinathan; Antonia Kolokythas; Shunli Chu; Yajun Geng; Yanmin Zhou; Xianghong Luan
Journal:  Biomed Res Int       Date:  2013-03-26       Impact factor: 3.411

10.  Clinical effectiveness of combining platelet rich fibrin with alloplastic bone substitute for the management of combined endodontic periodontal lesion.

Authors:  Lata Goyal
Journal:  Restor Dent Endod       Date:  2014-01-20
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  2 in total

1.  Autologous platelet-rich derivatives along with alloplastic bone substitute in the management of complex perio-endo cases.

Authors:  Lata Goyal; Namita Gupta; Narinder Dev Gupta
Journal:  J Indian Soc Periodontol       Date:  2020-03-02

Review 2.  The Adjunctive Use of Leucocyte- and Platelet-Rich Fibrin in Periodontal Endosseous and Furcation Defects: A Systematic Review and Meta-Analysis.

Authors:  Eudoxie Pepelassi; Maria Deligianni
Journal:  Materials (Basel)       Date:  2022-03-11       Impact factor: 3.623

  2 in total

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